3 documents found, page 1 of 1
A sulfated-polysaccharide fraction from seaweed gracilaria birdiae prevents nap...
Silva, Renan O.; Santana, Ana Paula M.; Carvalho, Nathalia S.; Bezerra, Talita S.; Oliveira, Camila B.; Damasceno, Samara Rodrigues BonfimAbstract: Red seaweeds synthesize a great variety of sulfated galactans. Sulfated polysaccharides (PLSs) from seaweed are comprised of substances with pharmaceutical and biomedical potential. The aim of the present study was to evaluate the protective effect of the PLS fraction extracted from the seaweed Gracilaria birdiae in rats with naproxen-induced gastrointestinal damage. Male Wistar rats were pretreated w...
Role of the NO/KATP pathway in the protective effect of a sulfated-polysacchari...
Damasceno, Samara Rodrigues Bonfim; Rodrigues, Jocélia C.; Silva, Renan O.; Nicolau, Lucas Antonio Duarte; Chaves, Luciano S.; Freitas, Ana L. P.Seaweeds are the most abundant source of polysaccharides such as alginates and agar, as well as carrageenans. This study aimed to investigate the gastroprotective activity and the mechanism underlying this activity of a sulfated-polysaccharide fraction extracted from the algae Hypnea musciformis (Wulfen) J.V. Lamour. (Gigartinales– Rhodophyta). Mice were treated with sulfated-polysaccharide fraction (3, 10, 30,...
Polysaccharide isolated from Agardhiella ramosissima : chemical structure and a...
Batista, Jalles A.; Dias, Eulina G.N.; Brito, Tarcisio V.; Prudêncio, Rafael S.; Silva, Renan O.; Ribeiro, Ronaldo A.; Souza, Marcellus Henrique L.P.The sulfated polysaccharide (PLS) fraction of Agardhiella ramosissima was characterized by microanalysis, infrared spectroscopy, NMR and gas–liquid-chromatography–mass-spectrometry. The main constituent of PLS was the carrageenan. The monosaccharide composition of the PLS showed galactose, 3,6- anhydrogalactose and 6-O-methylgalactose. The PLS (30 mg kg−1) significantly reduced the paw oedema induced by carrage...