Objective: The objective was to evaluate depressive symptoms, sleep alterations and the role of gender and obesity in obstructive sleep apnea (OSA) patients. Methods: Patients (N=140; 92 males and 48 female; age 54.6±8.2 years), submitted to polysomnography for suspected OSA, were assessed by the 17-item Hamilton Rating Scale for Depression (HRSD), Charlson comorbidity index (CCI) and Epworth Sleepiness Scale (...