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Antifungal Efficacy of Amphotericin B in Candida Albicans Endocarditis Therapy:...

Bezerra,Lucas Soares; Silva,Janielli Assis da; Santos-Veloso,Marcelo Antônio Oliveira; Lima,Sandro Gonçalves de; Chaves-Markman,Ândrea Virgínia

Abstract Introduction: Although it is the most common agent among the fungal causes of endocarditis, Candida albicans endocarditis is rare. Objective: To evaluate the efficacy of amphotericin B in the treatment of C. albicans endocarditis beyond a systematic review. Data search: Articles in English, Spanish and Portuguese, conducted in the following databases: MEDLINE, LILACS, IBECS and SciELO, in humans and pu...

Date: 2020   |   Origin: Oasisbr

GLA Gene Mutation in Hypertrophic Cardiomyopathy with a New Variant Description...

Chaves-Markman,Ândrea Virgínia; Markman,Manuel; Calado,Eveline Barros; Pires,Ricardo Flores; Santos-Veloso,Marcelo Antônio Oliveira

Abstract Background: Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations in the alpha galactosidase A gene (GLA) that lead to the enzymatic deficiency of alpha galactosidase (α-Gal A), resulting in the accumulation of globotriaosylceramide (Gb3) and globotriaosylsphingosine (lyso-Gb3), causing multiple organ dysfunctions. Objective: To perform GLA gene screening in a group of patien...

Date: 2019   |   Origin: Oasisbr

Prevalence of depression and anxiety and their association with cardiovascular ...

Santos-Veloso,Marcelo Antônio Oliveira; Melo,Maria Isa Souza Lacerda de; Cavalcanti,Roberta Azevedo Neves; Bezerra,Lucas Soares

SUMMARY BACKGROUND: Depression and anxiety disorders (DAD) are the most prevalent mental health conditions worldwide. Among the adult population served in basic care, it is estimated that depression affects about 14.3% of these individuals worldwide, and between 21.4% and 31% in Brasil. Anxiety affects up to 33.7% of the population during their lifetimes. OBJECTIVES: estimate the prevalence proportions of DAD a...

Date: 2019   |   Origin: Oasisbr

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