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Evaluation of the anti-inflammatory activity of riparin II (O-methil- N-2-hidro...

Carvalho, Alyne Mara Rodrigues de; Rocha, Nayrton Flávio Moura; Vasconcelos, Leonardo Freire; Rios, Emiliano Ricardo Vasconcelos; Dias, Marília Leite

Riparin II (RipII), an alkamide isolated from the green fruit of Aniba riparia, was tested in the various animal models of inflammation to investigate its anti-inflammatory activity. Male Wistar rats (180–240 g) were treated with RipII by gavage at doses 25 or 50 mg/kg, before initiating the inflammatory responses. The tests used were paw edema induced by carrageenan, dextran, histamine or serotonin; peritoniti...

Date: 2014   |   Origin: Oasisbr

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