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Sulforaphane prevents age-associated cardiac and muscular dysfunction through N...

Bose, C; Alves, I; Singh, P; Palade, PT; Carvalho, E; Børsheim, E; Jun, SR; Cheema, A; Boerma, M; Awasthi, S; Singh, SP

Age-associated mitochondrial dysfunction and oxidative damage are primary causes for multiple health problems including sarcopenia and cardiovascular disease (CVD). Though the role of Nrf2, a transcription factor that regulates cytoprotective gene expression, in myopathy remains poorly defined, it has shown beneficial properties in both sarcopenia and CVD. Sulforaphane (SFN), a natural compound Nrf2-related act...


Association of statin pretreatment with collateral circulation and final infarc...

Malhotra, K; Safouris, A; Goyal, N; Arthur, A; Liebeskind, DS; Katsanos, AH; Sargento-Freitas, J; Ribo, M; Molina, C; Chung, JW; Bang, OY; Magoufis, G

Statin pretreatment (SP) is associated with improved outcomes in acute ischemic stroke (AIS) patients. Collateral circulation status and final infarct volume (FIV) are independent predictors of functional outcome in AIS.


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