5 documents found, page 1 of 1
Unveiling new secrets in Parkinson's disease
Chegão, Ana; Vicente Miranda, HugoFunding Information: This study was supported by iNOVA4Health UID/Multi/04462/2013 – UIDB/04462/2020 and UIDP/04462/2020 , a program financially supported by Fundação para a Ciência e a Tecnologia (FCT) / Ministério da Ciência, Tecnologia e Ensino Superior, through national funds; and by Sociedade Portuguesa de Diabetologia . AC was supported by PD/BD/136863/2018 , FCT.; We are witnessing a considerable increas...
Dysmetabolism and Neurodegeneration
Capucho, Adriana M.; Chegão, Ana; Martins, Fátima O.; Miranda, Hugo Vicente; V Conde, SilviaFunding Information: Funding: AC and FOM were supported by grants and contracts from the Portuguese Foundation for Science and Technology, PD/BD/136863/2018 and CEECIND/04266/2017, respectively.; Accumulating evidence suggests the existence of a strong link between metabolic syndrome and neurodegeneration. Indeed, epidemiologic studies have described solid associations between metabolic syndrome and neurodegene...
Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease...
Chegão, Ana; Guarda, Mariana; Alexandre, Bruno M.; Shvachiy, Liana; Temido-Ferreira, Mariana; Marques-Morgado, Inês; Fernandes Gomes, BárbaraFunding Information: This study was supported by Fundação para a Ciência e Tecnologia (FCT) PTDC/NEU-OSD/5644/2014, by iNOVA4Health UIDB/04462/2020 and UIDP/04462/2020, a program financially supported by FCT/Ministério da Ciência, Tecnologia e Ensino Superior, through national funds; and by Sociedade Portuguesa de Diabetologia. The authors were supported by: A.C. (FCT, PD/BD/136863/2018; ProRegeM – PhD programm...
Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein
Vicente Miranda, Hugo; Chegão, Ana; Oliveira, Márcia S.; Fernandes Gomes, Bárbara; Enguita, Francisco J.; Outeiro, Tiago FlemingFunding: This study was supported by Fundação para a Ciência e Tecnologia (FCT) PTDC/NEU-OSD/5644/2014 and EXPL/NEU-OSD/0606/2012. Authors were supported by: HVM (FCT, SFRH/BPD/109347/2015); MO (FCT, EXPL/ NEU-OSD/0606/2012); AC (FCT, PD/BD/136863/2018; ProRegeM—PhD program, mechanisms of disease and regenerative medicine); BFG (PTDC/NEU-OSD/5644/2014). TFO is supported an EU Joint Program—Neurodegenerative Dis...
Posttranslational modifications of blood-derived alpha-synuclein as biochemical...
Miranda, Hugo Vicente; Cássio, Rafaela; Correia-Guedes, Leonor; Gomes, Marcos António; Chegão, Ana; Miranda, Elisa; Soares, Tiago; Coelho, MiguelWe are thankful to the patients and participants for their kind participation and donation of samples. This study was supported by Fundacao para a Ciencia e Tecnologia (FCT) EXPL/NEU-OSD/0606/2012, PTDC/NEUOSD/5644/2014. Authors were supported by: HVM (FCT, SFRH/BPD/64702/2009, SFRH/BPD/109347/2015); MG (FCT, EXPL/NEU-OSD/0606/2012); TFO (DFG Center for Nanoscale Microscopy and Molecular Physiology of the Brain...