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Natural lipid nanoparticles extracted from Morus nigra L. leaves for targeted t...

Gao, Qiang; Chen, Nanx; Li, Baoyi; Zu, Menghang; Ma, Ya; Xu, Haiting; Zhu, Zhenhua; Reis, R. L.; Kundu, Subhas C; Xiao, Bo

The clinical application of conventional medications for hepatocellular carcinoma treatment has been severely restricted by their adverse effects and unsatisfactory therapeutic effectiveness. Inspired by the concept of â medicine food homologyâ , we extracted and purified natural exosome-like lipid nanoparticles (LNPs) from black mulberry (Morus nigra L.) leaves. The obtained MLNPs possessed a desirable hydrod...


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