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FROG analysis ensures the reproducibility of genome scale metabolic models

Raman, Karthik; Kratochvil, Miroslav; Olivier, Brett G.; Konig, Matthias; Sengupta, Pratyay; Baskaran, Dinesh Kumar Kuppa; Nguyen, Tung V N

Genome scale metabolic models (GEMs) and other constraint-based models (CBMs) play a pivotal role in understanding biological phenotypes and advancing research in areas like metabolic engineering, human disease modelling, drug discovery, and personalized medicine. Despite their growing application, a significant challenge remains in ensuring the reproducibility of GEMs, primarily due to inconsistent reporting a...


Comparison of short-segment monoaxial and polyaxial pedicle screw fixation comb...

Wang, Hongwei; Zhao, Yiwen; Mo, Zhongjun; Han, Jianda; Chen, Yu; Yu, Hailong; Wang, Qi; Liu, Jun; Li, Changqing; Zhou, Yue; Xiang, Liangbi

OBJECTIVES: No studies have compared monoaxial and polyaxial pedicle screws with regard to the von Mises stress of the instrumentation, intradiscal pressures of the adjacent segment and adjacent segment degeneration. METHODS: Short-segment monoaxial/polyaxial pedicle screw fixation techniques were compared using finite element methods, and the redistributed T11-L1 segment range of motion, largest maximal von Mi...

Date: 2017   |   Origin: Oasisbr

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