2 documents found, page 1 of 1
Studies on the formation and synthetic mechanism of related substance G in pota...
Jin, Xiaoqing; Cao, Guangxiang; Zhang, Xiaoxiao; Chen, Yuguo; Wang, Liang; Zhong, ChuanqingThe objective of this study was to investigate the formation and synthetic mechanism of related substance G in potassium clavulanate production. The impurity in the potassium clavulanate final product, with a retention time of 13.5 min, was confirmed as related substance G by high performance liquid chromatography-mass spectrometry/mass spectrometry. Related substance G analysis during the production of clavula...
Linkage disequilibrium and haplotype homozygosity in population samples genotyp...
Wang, Hui; Lin, Chia-Ho; Service, Susan; Chen, Yuguo; Freimer, Nelson; Sabatti, Chiara; Karayiorgou, Maria; Roos, J. Louw; Pretorious, HermanObjective: Analyze the information contained in homozygous haplotypes detected with high density genotyping. Methods: We analyze the genotypes of ∼2,500 markers on chr 22 in 12 population samples, each including 200 individuals. We develop a measure of disequilibrium based on haplotype homozygosity and an algorithm to identify genomic segments characterized by non-random homozygosity (NRH), taking into account ...