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Biological evaluation of naproxen–dehydrodipeptide conjugates with self-hydroge...
Moreira, Rute; Jervis, Peter John; Carvalho, André; Ferreira, Paula M. T.; Martins, J. A. R.; Valentão, Patrícia; Andrade, Paula B.; Pereira, David M.The use of peptide–drug conjugates is emerging as a powerful strategy for targeted drug delivery. Previously, we have found that peptides conjugated to a non-steroidal anti-inflammatory drug (NSAID), more specifically naproxen–dehydrodipeptide conjugates, readily form nanostructured fibrilar supramolecular hydrogels. These hydrogels were revealed as efficacious nano-carriers for drug delivery applications. More...
Date: 2020
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Origin: RepositóriUM - Universidade do Minho