7 documents found, page 1 of 1
Influence of galantamine in the inflammatory process and tissular lesions cause...
Camargo,Lucas Fadel; Pinheiro,Guilherme Donzalisky; Oliveira,Priscilla Bianca de; Losada,Daniele Moraes; Chagas,Eduardo Federighi BaisiAbstract INTRODUCTION: Trypanosoma cruzi infection triggers an inflammatory process with exacerbated production of cytokines that stimulate inflammatory and anti-inflammatory signals, including the efferent anti-inflammatory signal known as the anti-inflammatory cholinergic pathway. Thus, the use of anticholinesterase drugs, such as galantamine, could minimize the inflammatory process caused by this disease. ME...
Oxidative stress among informal caregivers
Vasconcelos,Natália Ramos Imamura de; Dátilo,Gilsenir Maria Prevelato de Almeida; Chies,Agnaldo Bruno; Chagas,Eduardo Federighi BaisiAbstract Objective: to evaluate oxidative stress and non-enzymatic antioxidant defenses in informal caregivers, and correlations with anxiety, health satisfaction and quality of life. Method: a case-control analytical study was performed, where the case was represented by the main informal caregiver and the control was paired with individuals with identical characteristics to the case, but who were not informal...
Rivastigmine prevents injury induced by ischemia and reperfusion in rat liver
Chies,Agnaldo Bruno; Nakazato,Paula Carolina Grande; Spadella,Maria Angélica; Zorzi,Patrícia; Gomes,Maria Cecília JordaniAbstract Purpose: To evaluate whether pre-treatment with rivastigmine is able to attenuate the I/R induced lesions in rat liver. Methods: SHAM animals or those submitted to I/R, non-treated or pre-treated with rivastigminine (2mg/kg) either 50 or 15 minutes before ischemia, were used. After I/R protocol, these animals were killed and their livers were harvested to measurement of the mitochondrial swelling as we...
Prior intake of Brazil nuts attenuates renal injury induced by ischemia and rep...
Anselmo,Natassia Alberici; Paskakulis,Leticia Colombo; Garcias,Renata Correia; Botelho,Fernanda Fortuci Resende; Toledo,Giovana QuedaABSTRACT Introduction: Ischemia-reperfusion (IR) injury results from inflammation and oxidative stress, among other factors. Because of its anti-inflammatory and antioxidant properties, the Brazil nut (BN) might attenuate IR renal injury. Objective: The aim of the present study was to investigate whether the intake of BN prevents or reduces IR kidney injury and inflammation, improving renal function and decreas...
Effects of Continuous and Accumulated Exercise on Endothelial Function in Rat A...
Martinez,Juliana Edwiges; Taipeiro,Elane de Fátima; Chies,Agnaldo BrunoAbstract Background: The practice of exercise in short bouts repeated throughout the day may be an alternative strategy to lift people out of physical inactivity. Objective: to evaluate if accumulated exercise, as occurs in continuous exercise training, improve endothelial function in rat aorta. Methods: Wistar male rats were divided into three groups: continuous exercise (CEx, 1 hour on the treadmill) or accum...
Estresse Isolado ou Associado ao Etanol Libera Prostanóides em Aorta de Ratos v...
Baptista,Rafaela de Fátima Ferreira; Taipeiro,Elane de Fátima; Queiroz,Regina Helena Costa; Chies,Agnaldo Bruno; Cordellini,SandraFundamento: Estresse e etanol são ambos, independentemente, importantes fatores de risco cardiovascular. Objetivo: avaliar o risco cardiovascular do consumo de etanol e exposição ao estresse, isolados e em associação, em ratos machos adultos. Métodos: Os ratos foram separados em quatro grupos: controle, etanol (20% na água de beber durante seis semanas), estresse (imobilização 1h dia/5 dias por semana/ 6 semana...
Effects of hyperbaric oxygen therapy as hepatic preconditioning in rats submitt...
Losada,Daniele Moraes; Chies,Agnaldo Bruno; Feres,Omar; Chaib,Eleazar; D'Albuquerque,Luiz Augusto Carneiro; Castro-e-Silva,OrlandoPURPOSE:To analyze the role of hyperbaric oxygen therapy as hepatic preconditioning in rats submitted to hepatic ischemia and reperfusion.METHODS:Wistar rats were randomly divided into three groups: SHAM, rats submitted to surgical stress without hepatic ischemia and reperfusion, I/R, rats submitted to total hepatic pedicle ischemia for 30 min, followed by 5 min of reperfusion; HBOI/R, rats submitted to 60 minu...