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Consistent Trajectories of Rhinitis Control and Treatment in 16,177 Weeks: The ...

Sousa‐Pinto, B; Schünemann, HJ; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Anto, JM; Klimek, L; Czarlewski, W; Mullol, J; Pfaar, O; Bedbrook, A; Brussino, L

Introduction: Data from mHealth apps can provide valuable information on rhinitis control and treatment patterns. However, in MASK-air®, these data have only been analyzed cross-sectionally, without considering the changes of symptoms over time. We analyzed data from MASK-air® longitudinally, clustering weeks according to reported rhinitis symptoms. Methods: We analyzed MASK-air® data, assessing the weeks for w...


Rhinitis Associated with Asthma is Distinct from Rhinitis Alone: The ARIA‐MeDAL...

Bousquet, J; Melén, E; Haahtela, T; Koppelman, GH; Togias, A; Valenta, R; Akdis, CA; Czarlewski, W; Rothenberg, M; Valiulis, A; Wickman, M; Akdis, M

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...


Digitally‐Enabled, Patient‐Centred Care in Rhinitis and Asthma Multimorbidity: ...

Bousquet, J; Anto, JM; Sousa‐Pinto, B; Czarlewski, W; Bedbrook, A; Haahtela, T; Klimek, L; Pfaar, O; Kuna, P; Kupczyk, M; Regateiro, FS; Samolinski, B

MASK-air® , a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Econo...


Comparison of Rhinitis Treatments Using MASK-air ® Data and Considering the Min...

Sousa‐Pinto, B; Schünemann, HJ; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Anto, JM; Klimek, L; Czarlewski, W; Mullol, J; Pfaar, O; Bedbrook, A; Brussino, L

Background: Different treatments exist for allergic rhinitis (AR), including pharmacotherapy and allergen immunotherapy (AIT), but they have not been compared using direct patient data (i.e., "real-world data"). We aimed to compare AR pharmacological treatments on (i) daily symptoms, (ii) frequency of use in co-medication, (iii) visual analogue scales (VASs) on allergy symptom control considering the minimal im...


Allergen Immunotherapy in MASK‐Air Users in Real‐Life: Results of a Bayesian Mi...

Sousa‐Pinto, B; Azevedo, LF; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Klimek, L; Czarlewski, W; Anto, JM; Bedbrook, A; Kvedariene, V; Ventura, MT

Background: Evidence regarding the effectiveness of allergen immunotherapy (AIT) on allergic rhinitis has been provided mostly by randomised controlled trials, with little data from real-life studies. Objective: To compare the reported control of allergic rhinitis symptoms in three groups of users of the MASK-air® app: those receiving sublingual AIT (SLIT), those receiving subcutaneous AIT (SCIT), and those rec...


Behavioural Patterns in Allergic Rhinitis Medication in Europe: A Study Using M...

Sousa‐Pinto, B; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Klimek, L; Czarlewski, W; Antó, JM; Pfaar, O; Bedbrook, A; Kvedariene, V; Ventura, MT; Ansotegui, IJ

Background: Co-medication is common among patients with allergic rhinitis (AR), but its dimension and patterns are unknown. This is particularly relevant since AR is understood differently across European countries, as reflected by rhinitis-related search patterns in Google Trends. This study aims to assess AR co-medication and its regional patterns in Europe, using real-world data. Methods: We analysed 2015-20...


ARIA-EAACI Care Pathways for Allergen Immunotherapy in Respiratory Allergy

Bousquet, J; Pfaar, O; Agache, I; Bedbrook, A; Akdis, CA; Canonica, GW; Chivato, T; Al-Ahmad, M; Abdul Latiff, AH; Ansotegui, IJ; Bachert, C


COVID-19 Pandemic: Practical Considerations on the Organization of an Allergy C...

Pfaar, O; Klimek, L; Jutel, M; Akdis, CA; Bousquet, J; Breiteneder, H; Chinthrajah, S; Diamant, Z; Eiwegger, T; Fokkens, WJ; Fritsch, HW; Nadeau, KC

The coronavirus disease 2019 (COVID-19) has evolved into a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). Allergists and other healthcare providers (HCPs) in the field of allergies and associated airway diseases are on the front line, taking care of patients potentially infected with SARS-CoV-2. Hence, strategies and practices to minimize risks of infe...


ARIA 2016: Care pathways implementing emerging technologies for predictive medi...

Bousquet, J; Hellings, PW; Agache, I; Bedbrook, A; Bachert, C; Bergmann, KC; Bewick, M; Bindslev-Jensen, C; Bosnic-Anticevitch, S; Bucca, C; Caimmi, DP

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA-disseminated and im...


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