139 documents found, page 1 of 14
Discovery of (E)-4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist th...
Dutra, Luiz A. [UNESP]; Lacerda, Mariella G.; Destro Inácio, Maiara [UNESP]; Martins, Johnny W.L. [UNESP]; Lopes Silva, Ana C. [UNESP]Made available in DSpace on 2022-04-29T08:46:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Peroxisome proliferator-activated receptors are promising therapeutic targets for metabolic diseases, including obesity, diabetes, and dyslipidemia. This study describes the design, synthesis and pharmacological evaluation of stilbene-based compounds as dual PPARα/γ partial agonists with potency in the ...
Evaluation of preservative effectiveness of liquid crystalline systems with ret...
Chorilli, Marlus [UNESP]; Leonardi, Gislaine Ricci; Salgado, Hérida Regina Nunes [UNESP]; Scarpa, Maria Virgínia [UNESP]Made available in DSpace on 2022-04-29T08:48:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-01-01; The objective of this work was to evaluate the preservative effectiveness of liquid crystalline systems containing retynil palmitate (RP) by the challenge test (CT) and D-value. A system was developed containing water, silicon glycol copolymer, and polyether functional siloxane with 1% RP added. The ana...
Atividade antioxidante do extrato seco de cacau orgânico (theobroma cacao)-Estu...
e Silva, Silas Arandas Monteiro; Valarini, Michele Fernanda Costa; Chorilli, Marlus [UNESP]; Venturini, Anna; Leonardi, Gislaine RicciMade available in DSpace on 2022-04-29T09:35:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-01; The cocoa fruit (Theobroma cacao) is known worldwide for its richness in fatty acids and phenolic compounds, with antioxidant power, and it is known to be composed of more than 50% medium-chain fatty acids, making it a raw material that could be exploited by the food, pharmaceutical and cosmetics indust...
Bioadhesive curcumin-mediated photodynamic inactivation and its potential to ca...
Reina, Bárbara Donadon [UNESP]; Neto, Carolina Santezi; Garcia, Patrícia Petromilli Nordi Sasso [UNESP]; Chorilli, Marlus [UNESP]Made available in DSpace on 2022-04-29T08:33:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Curcumin-mediated Photodynamic Inactivation (PDI) has shown great potential to disinfect specific sites on tooth enamel but may involve contact with restorative materials. Thus, before use in dentistry, it is necessary to investigate whether...
Cellulose nanofibers improve the performance of retrograded starch/pectin micro...
Meneguin, Andréia Bagliotti [UNESP]; Sábio, Rafael Miguel [UNESP]; de Souza, Maurício Palmeira Chaves [UNESP]; Fernandes, Richard Perosa [UNESP]Made available in DSpace on 2022-04-29T08:33:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Cellulose nanofibers (CNF) were employed as the nanoreinforcement of a retrograded starch/pectin (RS/P) excipient to optimize its colon-specific properties. Although starc...
Validation of an innovative analytical method for simultaneous quantification o...
Araujo, Victor Hugo Sousa [UNESP]; Fernandes, Lígia de Souza [UNESP]; dos Reis, Leidiana Rocha [UNESP]; Carvalho, Gabriela Corrêa [UNESP]Made available in DSpace on 2022-04-29T08:34:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Vulvovaginal candidiasis is a public health problem with a high incidence among female patients. Currently, there is an increase in the identification of Candida spp. resistant to current therapy, making it necessary to search for new therapeutic alternatives. The synergistic potential of curcumin with ...
Miniaturized Microbiological Method to Determine the Potency of Rifaximin in Ta...
Correa, Clara Bersi Motta [UNESP]; Kogawa, Ana Carolina; Chorilli, Marlus [UNESP]; Salgado, Hérida Regina Nunes [UNESP]Made available in DSpace on 2022-04-29T08:35:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-20; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); BACKGROUND: Rifaximin, a semi-synthetic antimicrobial, does not present microbiological method described in official compendia, and there is a lack of literature on this topic. The quality control of antimicrobials is extremely important to ...
Effect of curcumin-encapsulated Pluronic® F-127 over duo-species biofilm of Str...
dos Santos, Diego Dantas Lopes [UNESP]; Besegato, João Felipe [UNESP]; de Melo, Priscila Borges Gobbo [UNESP]; Junior, João Augusto Oshiro [UNESP]Made available in DSpace on 2022-04-29T08:35:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01; To assess the effect of curcumin-encapsulated Pluronic® F-127 (Cur-Plu) during antimicrobial photodynamic therapy (aPDT) over duo-species biofilm of Streptococcus mutans and Candida albicans. Thermal analysis, optical absorption, and fluorescence spectroscopy were evaluated. Minimum inhibitory concentra...
Novel transdermal bioadhesive surfactant-based system for release and solubilit...
Volpe-Zanutto, Fabiana; Fonseca-Santos, Bruno [UNESP]; McKenna, Peter E.; Paredes, Alejandro J; Dávila, José Luis; McCrudden, Maelíosa T. C.Made available in DSpace on 2022-04-29T08:35:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Artemether (ART) and lumefantrine (LUM) are the gold standard antimalarial drugs used for the treatment of malaria in children and pregnant women. Typically, ART and LUM are delivered orally in the form of a combined tablet, however, the appropriateness of this route of administration for these drugs is...
Galleria mellonella for systemic assessment of anti-Candida auris using amphote...
Marena, Gabriel Davi [UNESP]; Ramos, Matheus Aparecido Dos Santos [UNESP]; Lima, Laura Caminitti [UNESP]; Chorilli, Marlus [UNESP]Made available in DSpace on 2022-04-29T08:35:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-10; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Galleria mellonella is a model that uses adult larvae to assess the prophylactic, therapeutic, and acu...