2 documents found, page 1 of 1
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage
Connolly, SJ; Sharma, M; Cohen, AT; Demchuk, AM; Czlonkowska, A; Lindgren, AG; Molina, CA; Bereczki, D; Toni, D; Seiffge, DJ; Tanne, D; Sandset, EC"Background: Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. Methods: We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an acute intrac...
Global, regional, and national age-sex-specific mortality for 282 causes of dea...
Roth, GA; Abate, D; Abate, KH; Abay, SM; Abbafati, C; Abbasi, N; Abbastabar, H; Abd-Allah, L; Abdela, J; Abdelalim, A; Abdollahpour, I; Abdulkader, RSBackground Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly availa...