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Liquid biopsy can detect BRCA2 gene variants in female dogs with mammary neoplasia
de Oliveira, Jéssica Rodrigues [UNESP]; Colombo, Jucimara; Gonçalves, Francine Moraes; de Carvalho, Lucas Amoroso Lopes [UNESP]; Costa, Douglas SantosMade available in DSpace on 2022-04-29T08:33:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Mammary tumours (MT) are one of the most prevalent malignancies in female dogs and women. Currently, molecular analyzes have shown that each tumour type presents its own genetic signature. In this context, liquid biopsy allows a comprehensiv...
Liquid biopsy as a diagnostic and prognostic tool for women and female dogs wit...
Colombo, Jucimara; Moschetta-Pinheiro, Marina Gobbe; Novais, Adriana Alonso; Stoppe, Bruna Ribeiro; Bonini, Enrico Dumbra; Gonçalves, Francine MoraesMade available in DSpace on 2022-05-01T09:47:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Introduction: Breast cancer (BC) is the malignant neoplasm with the highest mortality rate in women and female dogs are good models to study BC. Objective: We investigated the efficacy of liquid biopsy to detect gene mutations in the diagnos...
Hepatocellular carcinoma and miRNAs: An in silico approach revealing potential ...
Chuffa, Luiz Gustavo de Almeida [UNESP]; de Souza, Milena Cremer; Cruz, Ellen Mayara Souza; Ferreira, Francielle BelinelliMade available in DSpace on 2022-05-01T15:46:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-05-01; Background: Identifying innovative and effective therapeutic agents is imperative for treating hepatocellular carcinoma (HCC). Natural phytochemical compounds may be a feasible glimmer of hope as more than 8,000 phenolic structures are currently known, and several of them are efficient in treating diffe...
Maternal Protein Restriction Modulates Angiogenesis and AQP9 Expression Leading...
de Mello Santos, Talita [UNESP]; Cavariani, Marilia Martins [UNESP]; Pereira, Dhrielly Natália [UNESP]; Schimming, Bruno César [UNESP]Made available in DSpace on 2020-12-12T02:28:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-09-17; The maternal nutritional status is essential to the health and well-being of the fetus. Maternal protein restriction during the perinatal stage causes sperm alterations in the offspring that are associated with epididymal dysfunctions. Vascular endothelial growth factor (VEGF) and its receptor, VEGFr-2,...
Mimicking the tumor microenvironment: Fibroblasts reduce miR-29b expression and...
Medeiros, Mariana [UNESP]; Ribeiro, Amanda Oliveira [UNESP]; Lupi, Luiz Antônio [UNESP]; Romualdo, Guilherme Ribeiro [UNESP]; Pinhal, Danillo [UNESP]Made available in DSpace on 2019-10-06T17:11:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-13; Ovarian cancer (OC) is a highly prevalent gynecological malignancy worldwide. Throughout ovarian carcinogenesis, the crosstalk between cellular components of the microenvironment, including tumor cells and fibroblasts, is proposed to play critical roles in cancer progression. The dysregulation of microR...
Sex steroid receptors and apoptosis-related proteins are differentially express...
Chuffa, Luiz Gustavo de Almeida [UNESP]; Lupi Júnior, Luiz Antonio [UNESP]; da Maia Lima, Alfredo Feio [UNESP]Made available in DSpace on 2018-12-11T17:26:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-09-10; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); In Polycystic Ovaries (PCOs), the dynamics of sex hormone receptors and follicle-related apoptotic signaling remain unknown. In this study, we investigated the expression o...
Melatonin attenuates the TLR4-mediated inflammatory response through MyD88-and ...
Chuffa, Luiz Gustavo de Almeida [UNESP]; Fioruci-Fontanelli, Beatriz Aparecida [UNESP]; Mendes, Leonardo de Oliveira [UNESP]Made available in DSpace on 2015-10-21T13:10:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-02-06. Added 1 bitstream(s) on 2015-10-22T09:52:27Z : No. of bitstreams: 1 WOS000349182200001.pdf: 3113951 bytes, checksum: daa69c0f5f40f6d26c11ad314a8dbb4f (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Background: Toll-like receptors (TLRs) are effector molecules expressed on the surfa...
Melatonin attenuates Her-2, p38 MAPK, p-AKT, and mTOR levels in ovarian carcino...
Ferreira, Grazielle M. [UNESP]; Martinez, Marcelo; Camargo, Isabel Cristina Cherici [UNESP]; Domeniconi, Raquel F. [UNESP]Made available in DSpace on 2015-08-21T17:53:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2014. Added 1 bitstream(s) on 2015-08-24T14:41:51Z : No. of bitstreams: 1 ISSN1837-9664-2014-05-09-728-735.pdf: 1433916 bytes, checksum: 66899a205503d3f5a049c45e7cc71975 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Epidermal growth factor receptors 2 (Her-2) and 4 (Her-4) are closely associ...