3 documents found, page 1 of 1
Chimeric Antigen Receptor T‐Cell Therapy: Potentially Nephrotoxic?
Alferes, Daniela; Coelho, Inês; Ferreira, Hugo; Chuva, Teresa; Paiva, Ana; Chacim, Sérgio; Mariz, José Mário; Maximino Costa, JoséIntroduction: Chimeric antigen receptor (CAR) T‐cell therapy is an effective new treatment for hematologic malignan‐ cies. In this study, we aimed to characterize the acute kidney injury (AKI) and electrolyte disorders among adults with refractory and relapsed haematological malignancies treated with CAR‐T therapy and explore clinical outcomes. Methods: A retrospective, observational study was performed. Adult ...
Severe acute kidney injury in hospitalized cancer patients: epidemiology and pr...
Marques, Roberto Calças; Reis, Marina; Pimenta, Gonçalo; Sala, Inês; Chuva, Teresa; Coelho, Inês; Ferreira, Hugo; Paiva, Ana; Costa, José MaximinoBackground: Acute kidney injury (AKI) is a common complication among cancer patients, often leading to longer hospital stays, discontinuation of cancer treatment, and a poor prognosis. This study aims to provide insight into the incidence of severe AKI in this population and identify the risk factors associated with renal replacement therapy (RRT) and in-hospital mortality. Methods: This retrospective cohort st...
Acute kidney injury after cytoreductive surgery and hyperthermic intraperitonea...
Carias, Eduarda; Ferreira, Hugo; Chuva, Teresa; Paiva, Ana; Maximino, JoseBackground: Acute kidney injury (AKI) after cytoreductive surgery followed by the infusion of hyperthermic intraperitoneal chemothera-py (CRS/HIPEC) is associated with a higher rate of major complica-tions, resulting in prolonged hospitalization and increased mortality. Our objective was to evaluate the incidence of AKI and further pro-gression to chronic kidney disease (CKD) in patients submitted to this proce...