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Mitochondria as central hubs in synaptic modulation
Duarte, Filipe V.; Ciampi, Daniele; Duarte, Carlos B.Mitochondria are present in the pre- and post-synaptic regions, providing the energy required for the activity of these very specialized neuronal compartments. Biogenesis of synaptic mitochondria takes place in the cell body, and these organelles are then transported to the synapse by motor proteins that carry their cargo along microtubule tracks. The transport of mitochondria along neurites is a highly regulat...
Date: 2023
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Origin: Estudo Geral - Universidade de Coimbra