16 documents found, page 1 of 2
Alterations in myocardial collagen content affect rat papillary muscle function
Matsubara, Luiz S. [UNESP]; Matsubara, Beatriz B. [UNESP]; Okoshi, Marina P. [UNESP]; Cicogna, Antonio C. [UNESP]; Janicki, Joseph S.Made available in DSpace on 2022-04-28T19:54:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2000-01-01; We investigated the influence of myocardial collagen volume fraction (CVF, %) and hydroxyproline concentration (μg/mg) on rat papillary muscle function. Collagen excess was obtained in 10 rats with unilateral renal ischemia for 5 wk followed by 3-wk treatment with ramipril (20 mg·kg-1·day-1) (RHTR rats;...
Aerobic Exercise During Advance Stage of Uncontrolled Arterial Hypertension
Pagan, Luana U. [UNESP]; Gomes, Mariana J. [UNESP]; Damatto, Ricardo L.; Lima, Aline R. R. [UNESP]; Cezar, Marcelo D. M.; Damatto, Felipe C. [UNESP]Made available in DSpace on 2022-04-29T08:45:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-03; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Estadual Paulista; Aim: To evaluate the influence of physical training on myocardial function, oxidative stress, energy metabolism, and MAPKs and NF-κB signal...
Direct Effects of Colchicine on Myocardial Function: Studies in Hypertrophied a...
Cicogna, Antonio C. [UNESP]; Robinson, Kathleen G. [UNESP]; Conrad, Chester H. [UNESP]; Singh, Krishna [UNESP]; Squire, Robyn [UNESP]Made available in DSpace on 2022-04-29T08:46:55Z (GMT). No. of bitstreams: 0 Previous issue date: 1999-01-01; The aging spontaneously hypertensive rat (SHR) is a model in which the transition from chronic stable left ventricular hypertrophy to overt heart failure can be observed. Although the mechanisms for impaired function in hypertrophied and failing cardiac muscle from the SHR have been studied, none accoun...
Hypertrophied myocardium is more dependent on extracellular calcium than the no...
de Barros, Reginaldo [UNESP]; Zornoff, Leonardo A. M. [UNESP]; Ribeiro, Henrique B. [UNESP]; Okoshi, Marina P. [UNESP]; Padovani, Carlos R. [UNESP]Made available in DSpace on 2022-04-29T08:48:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-08-13; Background: The aim of this study was to analyze stable hypertrophied myocardial function and its response to inotropic maneuvers in rats submitted to renovascular hypertension for a 10-week period (RHT group, n=10). Material/Methods: Myocardial performance was studied in isolated left ventricle papilla...
AT1 receptor blockade attenuates insulin resistance and myocardial remodeling i...
Oliveira-Junior, Silvio A. [UNESP]; Martinez, Paula F. [UNESP]; Guizoni, Danielle M. [UNESP]; Campos, Dijon H. S. [UNESP]; Fernandes, TiagoMade available in DSpace on 2022-04-29T10:20:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-01-23; Background: Although obesity has been associated with metabolic and cardiac disturbances, the carrier mechanisms for these responses are poorly understood. This study analyzed whether angiotensin II blockade attenuates metabolic and cardiovascular disorders in rats with diet-induced obesity. Material an...
Misclassification probability as obese or lean in hypercaloric and normocaloric...
Nascimento, André F. [UNESP]; Sugizaki, Mário M. [UNESP]; Leopoldo, André S. [UNESP]; Lima-Leopoldo, Ana P. [UNESP]; Nogueira, Célia R. [UNESP]Made available in DSpace on 2022-04-28T20:51:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-01-01; The aim of the present study was to determine the classification error probabilities, as lean or obese, in hypercaloric diet-induced obesity, which depends on the variable used to characterize animal obesity. In addition, the misclassification probabilities in animals submitted to normocaloric diet were...
Differential nutritional, endocrine, and cardiovascular effects in obesity-pron...
Oliveira Junior, Silvio A. [UNESP]; Pai-Silva, Maeli Dal; Martinez, Paula F. [UNESP]; Campos, Dijon H. S. [UNESP]; Lima-Leopoldo, Ana P. [UNESP]Made available in DSpace on 2022-04-28T21:11:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-07-01; Background: This study tested whether rats with obesity induced by a hypercaloric diet (HD) present higher nutritional, endocrine, and cardiovascular disturbances compared with counterparts with obesity induced by overfeeding of a standard diet. An additional objective was to compare the isolated influe...
Myocardial dysfunction and abnormalities in intracellular calcium handling in o...
Lima-Leopoldo, Ana Paula; Leopoldo, André S. [UNESP]; Sugizaki, Mário M.; Bruno, Alessandro [UNESP]; Nascimento, André F. [UNESP]Made available in DSpace on 2022-04-29T01:14:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-09-01; Background: Several mechanisms have been proposed to contribute to cardiac dysfunction in obesity models, such as alterations in calcium (Ca 2+) handling proteins and β-adrenergic receptors. Nevertheless, the role of these factors in the development of myocardial dysfunction induced by obesity is still ...
At1 receptor blockade improves myocardial functional performance in obesity
de Oliveira-Junior, Silvio Assis; Muzili, Nayara de Araújo; Carvalho, Marianna Rabelo de; Ota, Gabriel Elias; de Morais, Camila SouzaMade available in DSpace on 2020-12-12T02:25:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01. Added 1 bitstream(s) on 2021-07-15T14:38:14Z : No. of bitstreams: 1 S0066-782X2020000800017.pdf: 502858 bytes, checksum: e1b029f14b41863f4c3436fb44036e15 (MD5); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Back...
Landscape of heart proteome changes in a diet-induced obesity model
Vileigas, Danielle F. [UNESP]; Harman, Victoria M.; Freire, Paula P. [UNESP]; Marciano, Cecília L. C. [UNESP]; Sant’Ana, Paula G. [UNESP]Made available in DSpace on 2020-12-12T01:48:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Obesity is a pandemic associated with a high incidence of cardiovascular disease; however, the mechanisms are not fully elucidated. Proteomics may provide a more in-depth understanding of the pathophysiological mechanisms and contribute to t...