2 documents found, page 1 of 1
MicroMundo: citizen science and service-learning against antimicrobial resistance
Cid, Victor J.Background: As alerted by WHO and other global or local health agencies, antimicrobial resistance (AMR) poses a global threat to environmental, animal, and human health. Side to side with surveillance and action, research and education stand as basic pillars to collectively tackle the current AMR crisis. The discovery of new antimicrobial drugs or alternative strategies to fight infectious diseases is urgent. W...
A unified nomenclature and amino acid numbering for human PTEN
Pulido, Rafael; Baker, Suzanne J.; Barata, João T.; Carracedo, Arkaitz; Cid, Victor J.; Chin-Sang, Ian D.; Davé, Vrushank; den Hertog, JeroenThe tumor suppressor PTEN is a major brake for cell transformation, mainly due to its phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P3] phosphatase activity that directly counteracts the oncogenicity of phosphoinositide 3-kinase (PI3K). PTEN mutations are frequent in tumors and in the germ line of patients with tumor predisposition or with neurological or cognitive disorders, which makes the PTEN gene and ...