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Concomitant Nitrofurantoin-Induced Autoimmune Hepatitis and Interstitial Lung D...

Matos,Andreia Carvalho de; Macedo,Cristiane Pais; Mendes,Patrícia Afonso; Cipriano,Maria Augusta; Paiva,Artur; Simão,Adélia

Abstract Antibiotics are known to cause adverse reactions, but multiple organ involvement associated with nonspecific symptoms can lead to a delay in diagnosis. A definitive correlation between each toxin and its effects is difficult to establish due to concomitant potential toxins in the circulation. This article highlights an uncommon case of concomitant nitrofurantoin-induced autoimmune hepatitis and lung fi...

Date: 2022   |   Origin: SciELO Portugal

Hepatic Myxoid Leiomyoma: A Very Rare Tumor

Fraga,João; Oliveira,Rui Caetano; Terracciano,Luigi; Silva,Mário Rui; Cipriano,Maria Augusta

Introduction: Mesenchymal tumors of the liver are rare, and in this group, myxoid leiomyomas are even rarer. So far, only 2 cases have been reported in the literature. Case Presentation: We aim to report the case of a 16-year-old female with a large lesion on the right hepatic lobe, grossly composed of gelatinous and heterogeneous tissue. Discussion: Histological evaluation revealed a benign mesenchymal neoplas...

Date: 2020   |   Origin: SciELO Portugal

Neuroendocrine Carcinoma and Intracystic Papillary Neoplasm: A Rare Association...

Fraga,João; Oliveira,Rui Caetano; Alexandrino,Henrique; Cipriano,Maria Augusta

Neuroendocrine carcinoma of the gallbladder is a very rare neoplasia comprising only 0.2% of all the gastrointestinal neuroendocrine tumors. We present the case of an 85-yearold male with nonspecific gastrointestinal symptoms, progressive weight loss, and deterioration in the preceding 15 days. Imaging study showed a 5-cm polypoid mass localized at the gallbladder fundus, leading to a radical cholecystectomy. P...

Date: 2019   |   Origin: SciELO Portugal

Dasatinib-Induced Colitis in a Patient with Chronic Myelogenous Leukemia

Perdigoto,David N.; Lopes,Sandra; Portela,Francisco; Cipriano,Maria Augusta; Tomé,Luís

Date: 2018   |   Origin: SciELO Portugal

C3 glomerulopathy: a rare kidney histological presentation of multiple myeloma

Costa,Joana Silva; Romãozinho,Catarina; Rodrigues,Luís; Marinho,Carol; Sousa,Vitor; Pratas,Jorge; Cipriano,Maria Augusta; Alves,Rui

C3 Glomerulopathy is a rare disease caused by abnormal control of the alternative complement pathway, resulting in a predominant glomerular C3 deposition. Its association with multiple myeloma has been reported in recent literature. We present a case of a 66-year-old women, referred for a nephrology consultation with a stage 4 chronic kidney disease, microhematuria, leukocyturia, sub-nephrotic range proteinuria...

Date: 2018   |   Origin: SciELO Portugal

Uncertainties in the Management of a Lynch Syndrome Patient: A Case Report

Campos,Sara; Amaro,Pedro; Cunha,Inês; Fraga,João; Cipriano,Maria Augusta; Tomé,Luís

Introduction: Lynch syndrome (LS), the most common hereditary colorectal cancer syndrome, is characterized by mutations in mismatch repair (MMR) genes leading to an increased cancer risk, namely colorectal cancer. Case: In the context of surveillance colonoscopy, a 40-mm flat lesion (0-IIa+b, Paris classification) was identified and submitted to piecemeal mucosal endoscopic resection in a 64-year-old LS patient...

Date: 2017   |   Origin: SciELO Portugal

Skin Metastases: The Visible Face of a Disastrous Unusual Finding

Giestas,Sílvia; Casela,Adriano; Agostinho,Cláudia; Souto,Paulo; Camacho,Ernestina; Julião,M.; Cipriano,Maria Augusta; Sofia,Carlos

Date: 2016   |   Origin: SciELO Portugal

Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion i...

Abrantes,Carlos Filipe C.; Silva,Mário Rui; Oliveira,Rui Caetano; Eloy,Catarina; Cipriano,Maria Augusta; Castro,Lígia P.

ABSTRACT Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm that usually originates from abdominal soft tissues. A female patient aged 50 years presented with a 1.2 cm gallbladder polyp. The microscopic study showed spindle cell proliferation in an edematous background rich in lymphocytes and plasma cells. Immunohistochemistry showed positivity for vimentin, smooth muscle actin, and anapla...

Date: 2015   |   Origin: Oasisbr

Pancreatic metastasis from renal cell carcinoma: A different cause for recurren...

Correia,Tito Miguel; Almeida,Nuno Miguel; Torres-Oliveira,Ana Isabel; Velez,Ana; Oliveira,Pedro; Cipriano,Maria Augusta; Dias,Nuno

A 64-year-old man with a renal cell carcinoma (RCC) underwent right nephrectomy. There was no identifiable recurrence during follow-up. Six years after surgery he presented with melena and ferropenic anaemia. Endoscopic evaluation demonstrated a vascular lesion in duodenum and haemostasis was performed. However, the bleeding recurred and further endoscopies revealed an enlarged multilobulated infiltrative and u...

Date: 2014   |   Origin: SciELO Portugal

Hemangioendotelioma epitelióide hepático: um caso de rápida progressão

Duque,Gabriela; Souto,Paulo; Rosa,Albano; Rodrigues,Hélder; Silva,Mário Rui; Lopes,Sandra; Camacho,Ernestina; Monsanto,Pedro; Cipriano,Maria Augusta

O hemangioendotelioma epitelióide hepático (HEH) é um tumor vascular maligno raro, cujo potencial maligno é incerto. Os sinais e sintomas associados são mormente inespecíficos e a sua identificação é incidental. A heterogeneidade destes tumores nos métodos imagiológicos dificulta o seu diagnóstico e este só é estabelecido definitivamente pelo estudo anátomo-patológico. A estratégia terapêutica não está uniformi...

Date: 2013   |   Origin: SciELO Portugal

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