4 documents found, page 1 of 1
HBM4EU - Deliverable Report D 5.5: Human biomonitoring in risk assessment: 2nd ...
Santonen, Tiina; Mahiout, Selma; Bessems, J.; Buekers, J.; Baken, K.; Schoeters, G.; Woutersen, M.; Vermeire, T.; Bil, W.; Ougier, E.; Rousselle, C.The aim of this work was to exemplify the inclusion of human biomonitoring (HBM) data in risk assessment (RA) and health impact assessment (HIA) strategies. RA was performed for six compound groups on HBM4EU’s first list of priority substances: anilines, cadmium/chromium, flame retardants, PAHs, PFAS and phthalates. In addition, burden of disease (BoD) calculations were made for cadmium. The general approach us...
Improving risk assessment of chemicals by the use of human biomonitoring: HBM4E...
Santonen, T.; Alvito, P.; Bessems, J.; Borges, T.; Brunet, D.; Buekers, J.; Cornelis, C.; van Engelen, J.; Gonzalez Caballero, M. C.; Humar-Juric, T.The default approach in the risk assessment (RA) of chemicals is to assess external exposure by combining different sources and routes of exposure. This kind of approach contains various uncertainties and may overestimate exposure, since conservative estimates are needed due to the limited data on, for example, the absorption of the chemical and interspecies and intraspecies differences. Human biomonitoring (HB...
Human biomonitoring in risk assessment: analysis of the current practice and 1s...
Santonen, T.; Heinälä, M.; Bessems, J.; Buekers, J.; Cornelis, C.; Vermeire, T.; Woutersen, M.; van Engelen, J.; Borges, T.; Rousselle, C.; Ougier, E.In chemicals risk assessment frameworks, the default approach is to assess external intake from different sources of exposure and via different routes of exposure. They are often assessed separately. This approach includes various uncertainties and often overestimates the real uptake since default, conservative estimates are used e.g. for the absorption of the chemical. At the same time, actual (real life) expo...
Improving risk assessment of chemicals by the use of human biomonitoring - HBM4...
Santonen, T.; Alvito, Paula; Bessems, J.; Borges, T.; Brunet, D.; Buekers, J.; Cornelis, C.; van Engelen, J.; Gonzalez Caballero, M.C.; Humar-Juric, T.The default approach in the risk assessment (RA) of chemicals is to assess external exposure by combining different sources and routes of exposure. This kind of approach contains various uncertainties and may overestimate exposure, since conservative estimates are needed due to the limited data on, for example, the absorption of the chemical and interspecies and intraspecies differences. Human biomonitoring (HB...