10 documents found, page 1 of 1
Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes ...
Nicchio, Ingra G. [UNESP]; Cirelli, Thamiris [UNESP]; Nepomuceno, Rafael [UNESP]; Hidalgo, Marco A.R. [UNESP]; Rossa, Carlos [UNESP]Made available in DSpace on 2022-04-29T08:36:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Background. Type 2 diabetes mellitus (T2DM) and periodontitis (P) commonly occur as comorbidities, but the commonalities in the genetic makeup of affected individuals is largely unknown. Since dyslipidemia is a frequent condition in these individuals, we investigate the association of genomic variations...
Effect of Bacterial Infection on Ghrelin Receptor Regulation in Periodontal Cel...
Nogueira, Andressa V. B.; Nokhbehsaim, Marjan; Damanaki, Anna; Eick, Sigrun; Beisel-Memmert, Svenja; Kirschneck, Christian; Schröder, AgnesMade available in DSpace on 2022-04-29T08:40:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Deutscher Akademischer Austauschdienst; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); The effect of bacterial infection on the expression of growth hormone secretagogue receptor (GHS-R) was investigated in periodontal cells and tissues, and the actions of ghrelin were evaluated. G...
Validation in a Brazilian population of gene markers of periodontitis previousl...
Cirelli, Thamiris [UNESP]; Nepomuceno, Rafael [UNESP]; Orrico, Silvana R. P. [UNESP]; Rossa, Carlos [UNESP]; Cirelli, Joni A. [UNESP]; North, Kari E.Made available in DSpace on 2021-06-25T10:34:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Background: Bioinformatic tools and genome-wide association studies (GWAS) have led to comprehensive identification of single nucleotide polymorphisms (SNPs) associated with periodontitis in diverse populations. Here we aimed to detect and validate the association of seven SNPs as genetic markers of sus...
Association of type 2 diabetes mellitus and periodontal disease susceptibility ...
Cirelli, Thamiris [UNESP]; Nepomuceno, Rafael [UNESP]; Goveia, Jéssica Marina [UNESP]; Orrico, Silvana R. P. [UNESP]; Cirelli, Joni A. [UNESP]Made available in DSpace on 2021-06-25T10:48:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Objective: Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CDKN2B, RPSAP52, GPR45 HHEX, IL18, and RUNX2 genes associated with type 2 diabetes mellitus (T2DM) and/or periodontitis (P) in diverse populations, and we sought to ...
Polymorphisms and haplotypes in the Interleukin 17 Alfa gene: potential effect ...
Rimachi Hidalgo, Marco A. [UNESP]; Cirelli, Thamiris [UNESP]; da Silva, Bárbara Roque [UNESP]; Nicchio, Ingra Gagno [UNESP]; Nepomuceno, Rafael [UNESP]Made available in DSpace on 2021-06-25T10:52:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Few studies evaluate interrelationships between periodontitis (P) and Type 2 Diabetes Mellitus (T2DM). The aim of this study is to investigate the genetic susceptibility t...
Effect of electric, ultrasonic and manual toothbrushes on biofilm removal and g...
Cirelli, Thamiris [UNESP]; de Oliveira, Guilherme José Pimentel Lopes [UNESP]; Nogueira, Andressa Vilas Boas [UNESP]Made available in DSpace on 2021-06-25T10:53:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Aim: To evaluate the effect of manual (M), electric (E) and ultrasonic (US) toothbrushes on the removal of oral biofilm and control of gingivitis. Also, the roughness and tooth wear production were evaluated in vitro. Methods: For the...
Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated wit...
Cirelli, Thamiris [UNESP]; Nepomuceno, Rafael [UNESP]; Rios, Ana Cláudia S. [UNESP]; Orrico, Silvana R. P. [UNESP]; Cirelli, Joni A. [UNESP]Made available in DSpace on 2020-12-12T02:14:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Objective: To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A, IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes, “classically” related with periodontitis, could be associated with susceptibility to T2DM, and also with both diseases concomitantly. Background: There are common path...
Functional haplotype in the Interleukin8 (CXCL8) gene is associated with type 2...
Silva, Bárbara Roque da [UNESP]; Cirelli, Thamiris [UNESP]; Nepomuceno, Rafael [UNESP]; Theodoro, Letícia Helena [UNESP]; Orrico, Silvana R.P. [UNESP]Made available in DSpace on 2020-12-12T02:21:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background and aim: Type 2 Diabetes Mellitus (T2DM) and Periodontitis (P) are prevalent multifactorial disorders worldwide, sharing a bidirectional relationship influenced...
Absolute quantification of Aggregatibacter actinomycetemcomitans in patients ca...
Cirelli, Thamiris [UNESP]; Finoti, Livia S. [UNESP]; Corbi, Sâmia C.T. [UNESP]; Anovazzi, Giovana [UNESP]; Nepomuceno, Rafael [UNESP]Made available in DSpace on 2018-12-11T16:50:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); This study aimed to evaluate the association between haplotypes in the interleukin 8 (IL8) and IL4 genes previously associated to chronic periodontitis (CP) and the levels of Aggregatibacter actinomycetemcomitans (A.a.) in subgingival sites ...
Expression profile of genes potentially associated with adequate glycemic contr...
Corbi, Sâmia Cruz Tfaile [UNESP]; Bastos, Alliny Souza [UNESP]; Nepomuceno, Rafael [UNESP]; Cirelli, Thamiris [UNESP]; Santos, Raquel Alves DosMade available in DSpace on 2018-12-11T17:33:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Despite increasing research in type 2 diabetes mellitus (T2D), there are few studies showing the impact of the poor glycemic control on biological processes occurring in T2D. In order to identify potential genes related to poorly/well-controlled patients with T2D, our strategy of investigation included ...