Copyright © 2025 AME Publishing Company. All rights reserved.; BACKGROUND: The factors influencing bone healing in complete burst fractures-key to deciding between stabilization or vertebral replacement-remain poorly defined. Arterial vascularization and bone nutrition are known to affect healing or progression to necrosis. However, the role of vascular injury in vertebral fractures is not yet conclusively demo...
Publisher Copyright: © 2022 The Authors; Elemental content plays an important role in biological processes, and so, the multielemental analysis of human tissue samples is required in biomedical research. Still, the small amount of available biological samples and the adipose content of the samples can be major setbacks for the accurate determination of elemental content. In this study, we explored the potential...
Funding Information: This research was funded by the International Atomic Energy Agency under Research Contract No. 18202 (CRP F23030). Authors acknowledge FCT—Fundação para a Ciência e a Tecnologia I.P. for the national funds in the scope of the project UIDB/04349/2020+UIDP/04349/2020, UIDB/00100/2020 and UIDB/00329/2020. Publisher Copyright: © 2022 by the authors.; Frequently, deep partial and full-thickness ...
Funding Information: This work was supported by the European Community’s Horizon 2020 Program supported the MEDIRAD—Implications of Medical Low Dose Radiation Exposure granted by the Euratom Research and Training Program 2014-2014 under agreement No. 755523. The MS work was financed by the Portuguese Mass Spectrometry Network, integrated in the National Roadmap of Research Infrastructures of Strategic Relevance...
Publisher Copyright: Copyright © Ordem dos Médicos 2022; Introduction: The Portuguese experience in microsurgical reconstruction of the head and neck after oncological surgery is scantly described. The primary aim of this study was to characterize the use of microvascular reconstruction after head and neck tumor resection in a Portuguese tertiary oncological center Material and Methods: The authors retrospectiv...
PTDC/FIS-AQM/32536/2017 through FEDER and Fundacao para a CiEncia e Tecnologia (FCT) (Portugal) UID/FIS/04559/2019 to LIBPhys-UNL from the FCT/MCTES/PIDDAC, Portugal. Patricia M. S. Carvalho acknowledges the support of FCT (Portugal) under contract No. PD/BD/128324/2017.; Trace elements are present in minute amounts in the human body but contribute to its proper functioning, by participating in several biologic...
The knowledge about the required quantity of blood to irrigate an angiosome is important on ischemia (disruption on blood perfusion) prediction, diagnosis and treatment. An angiosome (or flap) is an anatomic unity (or flap) of tissue, it is constituted by skin, subcutaneous tissue and muscle, it is irrigated by an artery and drain by specific veins [1]. Since 70’s, flaps have been used on clinical practice for ...
INTRODUCTION: Calcaneal osteomyelitis poses a tough challenge for any reconstructive surgeon. The eradication of the infection and the reconstruction of the defect are the main goals of treatment. PRESENTATION OF CASE: We present the case of a 53-year-old male with chronic calcaneal osteomyelitis. The patient was submitted to several bone and soft tissue debridements and twice the application of gentamicin/sulf...
The main aim of this work was to study the usefulness of human β-defensins 2 (BD-2) and 3 (BD-3), which are part of the innate immune system, in the treatment of infected ischemic skin flaps. We investigated the effect of transducing rat ischemic skin flaps with lentiviral vectors encoding human BD-2, BD-3, or both BD-2 and BD-3, to increase flap survival in the context of a P. aeruginosa infection associated w...
INTRODUCTION: The aim of the present study is to report an original, unusual, case of bilateral anatomical variation of the sciatic nerve, with low origin and high division. MATERIAL AND METHODS: Anatomical dissection was performed on a 66 year-old female cadaver. The corpse was embalmed and conserved through our original embalming techniques. RESULTS: The particular anatomical variation was first detected duri...