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Production and characterization of a mouse monoclonal antibody against the Gag ...

Marcelino, JM; Novo, C; Pereira, JM; Picotez, F; Clemente, A; Taveira, N

One anticapsid (p26) mouse monoclonal antibody was developed after immunization with recombinant p26 Gag protein and was tested for reactivity with different HIV-1 and HIV-2 isolates by ELISA and Western blot analysis. This antibody, named R26.1, reacted

Date: 2001   |   Origin: Repositório da Universidade de Lisboa
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Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethy...

Clemente, A; Domingos, A; Grancho, AP; Iley, J; Moreira, R; Neres, J; Palma, N; Santana, AB; Valente, E

A series of N-acyloxymethyl- and N-aminocarbonyloxymethyl derivatives of 2-azetidinones. 3, with different substituent patterns at the beta -lactam C-3 and C-4 positions, were designed as potential mechanism-based inhibitors for human leukocyte elastase and found to exhibit inhibitory potency and selectivity for the enzyme, (C) 2001 Elsevier Science Ltd. All rights reserved.

Date: 2001   |   Origin: Repositório da Universidade de Lisboa
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N-Acyloxymethyl-2-azetidinones as Human Leukocyte Elastase Inhibitors

Santana, AB; Valente, E; Neres, J; Moreira, R; Palma, N; Grancho, AP; Domingos, A; Clemente, A; Iley, J

Date: 2000   |   Origin: Repositório da Universidade de Lisboa
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