14 documents found, page 1 of 2

Development and fabrication of a microfluidic device for mechanical characteriz...

This work reports the design and fabrication of a polymeric microfluidic device, with a hyperbolic contraction, to promote extensional flow and allow the single cell mechanical characterization, in vitro, of healthy and malaria-infected red blood cells (RBCs). The obtained results show an extensional flow profile of the velocity across the microchannel for both healthy and infected RBCs, while the ability of th...

Deep into the proteomic network of Plasmodium falciparum's lipocalin

Malaria, an infectious disease caused by Plasmodium parasites, threats half of the world's population yearly due to the parasite's ability to develop resistance to antimalarial drugs. Therefore, innovative intervention strategies, which rely on a deeper understanding of the parasite's complex biology are urgently needed. Most antimalarial drugs target the symptomatic stage of infection of the parasite that is t...

Deep into the proteomic network of hemozoin formation in the malaria parasite

Malaria is an infectious disease caused by Plasmodium parasites transmitted to and between people by mosquitoes. Despite progress in its control, malaria still threatens half of the world’s population yearly, owing to the capacity of the parasite to develop resistance to antimalarial drugs treatment. Thus, innovative intervention measures are urgent and strictly depend on our better understanding of the parasit...

O USO DAS TECNOLOGIAS DIGITAIS NO ENSINO DE FÍSICA: RECURSOS, PERCEPÇÕES E DESA...

Submitted by Yanna Sousa (yanna_gomes@yahoo.com.br) on 2021-07-16T22:32:16Z No. of bitstreams: 2 O USO DAS TECNOLOGIAS DIGITAIS NO ENSINO DE FÍSICA RECURSOS, PERCEPÇÕES E DESAFIOS_ Poliana Targino Batista.pdf: 599443 bytes, checksum: f9a6b191bbb474553ab5cc19047ac62d (MD5) Ata de Defesa_ Poliana Targino Batista.pdf: 359984 bytes, checksum: bb9ab6b706086917c38df95f6d662371 (MD5); Approved for entry into archive b...

A (R)EVOLUÇÃO DA EDUCAÇÃO 4.0 NO ENSINO DE CIÊNCIAS E MATEMÁTICA EM ESCOLAS DA ...

Submitted by Yanna Sousa (yanna_gomes@yahoo.com.br) on 2021-11-10T00:01:38Z No. of bitstreams: 2 ata de defesa_Priscila da Silva Santos.pdf: 137871 bytes, checksum: 421ad950fbc24dc143a016c561d76489 (MD5) A (R)EVOLUÇÃO DA EDUCAÇÃO 4.0 NO ENSINO DE CIÊNCIAS E MATEMÁTICA EM ESCOLAS DA REDE ESTADUAL DA PARAIBA_TCC.pdf: 549649 bytes, checksum: b6d80bf7224637d05edcb3d18e29f900 (MD5); Approved for entry into archive b...

Screening of dual chemo-photothermal cellular nanotherapies in organotypic brea...

Living therapeutics approaches that exploit mesenchymal stem cells (MSCs) as nanomedicine carriers are highly attractive due to MSCs native tropism toward the 3D tumor microenvironment. However, a streamlined pre-clinical evaluation of nano-in-cell anti-cancer therapies remains limited by the lack of in vitro testing platforms for screening MSCs-3D microtumor interactions. Herein we generated dense breast cance...

Labor Share Heterogeneity and Fiscal Consolidation Programs

We show that the labor share of income is an important factor affecting the mechanisms behind fiscal consolidation programs, thus requiring consideration when evaluating fiscal multipliers across countries. We calibrate a life-cycle, overlapping generations model to match key characteristics of different European economies and evaluate the recessive impacts of fiscal consolidation programs. We find a positive r...

Self-assembled bioactive colloidal gels as injectable multiparticle shedding pl...

Self-assembled colloidal gels are highly versatile 3D nanocluster platforms with potential to overcome the rapid clearing issues associated with standard free nanotherapeutics administration. However, the development of nanoassembled colloidal gels exhibiting autonomous multiparticle release from the bulk particle network remains elusive. Herein, we generated multiparticle colloidal gels from two nanosized buil...

Computational modelling of human lower limb for reproduction of walking dynamic...

This work comprises the use of a biomechanical model of the human lower limb proposed by Geyer and Herr in 2010 to study joint characteristic parameters throughout physiological and anterior cruciate ligament (ACL) pathological gait. The model kinematics when simulating healthy gait were in good agreement with literature. Regarding to the kinetics, the ankle joint torque was corroborated with literature, while ...

O ensino dos jogos desportivos coletivos de invasão segundo uma abordagem tátic...