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Wernicke's encephalopathy in a patient with non-Hodgkin's lymphoma post-Autolog...

Leitão,João Paulo de Vasconcelos; Lemes,Romélia Pinheiro Gonçalves; Barbosa,Maritza Cavalcante; Araújo,Beatriz Stela Gomes de Souza Pitombeira

SUMMARY Wernick's Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predi...

Date: 2018   |   Origin: Oasisbr

Relevance of prognostic factors in the decision-making of stem cell transplanta...

Duarte,Fernando Barroso; Santos,Talyta Ellen de Jesus dos; Barbosa,Maritza Cavalcante; Kaufman,Jacques; Vasconcelos,João Paulo de

ABSTRACT The hematopoietic stem cell transplantation (HSCT) is the only curative alternative for Myelodysplastic Syndrome (MDS), but many patients are not eligible for this treatment, as there are several limiting factors, especially in the case of patients with low-risk MDS. The aim of this study is to discuss the factors that can guide the decision-making on referring or not a patient to HSCT. Three cases of ...

Date: 2016   |   Origin: Oasisbr

T-cell/myeloid mixed-phenotype acute leukemia with monocytic differentiation an...

Lopes,Germison Silva; Leitão,João Paulo de Vasconcelos; Kaufman,Jacques; Duarte,Fernando Barroso; Matos,Daniel Mazza

Mixed phenotype acute leukemia is a rare subtype of leukemia that probably arises from a hematopoietic pluripotent stem cell. The co-expression of two of myeloid, B- or T-lymphoid antigens is the hallmark of this disease. Herein, the case of a 28-year-old female patient is reported who presented with hemoglobin of 5.8 g/dL, white blood cell count of 138 × 109/L and platelet count of 12 × 109/L. The differential...

Date: 2014   |   Origin: Oasisbr

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