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Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischem...
Sousa, Larissa Fonseca da Cunha; Coelho, Fernanda Matos; Rodrigues, David Henrique; Campos, Alline Cristina; Barcelos, Luciola da SilvaOBJECTIVE: Ischemic stroke may result from transient or permanent reductions of regional cerebral blood flow. Polymorphonuclear neutrophils have been described as the earliest inflammatory cells to arrive in ischemic tissue. CXCR1/2 receptors are involved in the recruitment of these cells. However, the contribution of these chemokine receptors during transient brain ischemia in mice remains poorly understood. I...
Date: 2013
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Origin: Oasisbr