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Relatório de Estágio - Clube de Montanhismo (Guarda)

Coelho, Hugo

Este relatório tem como objetivo adquirir o diploma do Curso Técnico Superior de Desportos de Montanha. O estágio realizou-se no Clube de montanhismo da Guarda e o seu tempo de duração foi de 750 horas, teve início dia 6 de fevereiro de 2023 e deu como terminado dia julho de 2023. O clube de montanhismo da Guarda tem uma vasta variada de atividades de natureza onde as atividades são realizadas tendo em conta o ...


Correction to: Collaborative immersive authoring tool for real-time creation of...

Coelho, Hugo; Melo, Miguel; Martins, José; Bessa, Maximino

In the original publication, Figs. 1 and 2 were interchange and the citation of Fig. 1 in the third paragraph of section 2.2 Authoring tools for multisensory VR experiences should be removed. The citation of Fig. 2 in section 3.1 System architecture should be changed to Fig. 1 and the citation of Fig. 1 in the same section should be change to Fig. 2. Also, the acknowledgement is missing in the original publicat...

Date: 2020   |   Origin: Biblioteca Digital do IPB

Collaborative immersive authoring tool for real-time creation of multisensory V...

Coelho, Hugo; Melo, Miguel; Martins, José; Bessa, Maximino

With the appearance of innovative virtual reality (VR) technologies, the need to create immersive content arose. Although there are already some non-immersive solutions to address immersive audio-visual content, there are no solutions that allow the creation of immersive multisensory content. This work proposes a novel architecture for a collaborative immersive tool that allows the creation of multisensory VR e...

Date: 2019   |   Origin: Biblioteca Digital do IPB

Combined genetic and epigenetic alterations of the TERT promoter affect clinica...

Leão, Ricardo; Lee, Donghyun; Figueiredo, Arnaldo; Hermanns, Thomas; Wild, Peter; Komosa, Martin; Lau, Irene; Mistry, Mathew; Nunes, Nuno Miguel

In urothelial bladder cancer (UBC), risk stratification remains an important unmet need. Limitless self-renewal, governed by TERT expression and telomerase activation, is crucial for cancer progression. Thus, telomerase activation through the interplay of mutations (TERTpMut ) and epigenetic alterations in the TERT promoter may provide further insight into UBC behavior. Here, we investigated the combined effect...


A cancer specific hypermethylation signature of the TERT promoter predicts bioc...

Castelo Branco, Pedro; Leão, Ricardo; Lipman, Tatiana; Campbell, Brittany; Lee, Donghyun; Price, Aryeh; Zhang, Cindy; Heidari, Abolfazl; Stephens, Derek

The identification of new biomarkers to differentiate between indolent and aggressive prostate tumors is an important unmet need. We examined the role of THOR (TERT Hypermethylated Oncological Region) as a diagnostic and prognostic biomarker in prostate cancer (PCa).We analyzed THOR in common cancers using genome-wide methylation arrays. Methylation status of the whole TERT gene in benign and malignant prostate...


A cancer specific hypermethylation signature of the TERT promoter predicts bioc...

Castelo-Branco, Pedro; Leao, Ricardo; Lipman, Tatiana; Campbell, Brittany; Lee, Donghyun; Price, Aryeh; Zhang, Cindy; Heidari, Abolfazl; Stephens, Derek

The identification of new biomarkers to differentiate between indolent and aggressive prostate tumors is an important unmet need. We examined the role of THOR (TERT Hypermethylated Oncological Region) as a diagnostic and prognostic biomarker in prostate cancer (PCa).We analyzed THOR in common cancers using genome-wide methylation arrays. Methylation status of the whole TERT gene in benign and malignant prostate...


Unclassified Sex Cord Testis Tumor

Grenha, Vânia; Serra, Paula; Coelho, Hugo; Retroz, Edson; Temido, Paulo; Mota, Alfredo

Unclassified sex cord testis tumor is an extremely rare tumor, especially in the adult. It is characterized histologically for a nonspecific combination of testis stromal and epithelial elements, with varying degree of differentiation. Treatment usually consists of radical orchiectomy followed by clinical and imaging surveillance. The available literature about this pathology relies almost exclusively on clinic...

Date: 2014   |   Origin: Acta Médica Portuguesa

Relatório de Estágio Curricular – Porto Canal (Matosinhos)

Coelho, Hugo

Este relatório é referente ao estágio curricular decorrido no Porto Canal, no âmbito do programa curricular da Licenciatura em Comunicação Multimédia, ministrado na Escola Superior de Educação Comunicação e Desporto do Instituto Politécnico da Guarda. Com a duração três meses, o estágio foi realizado de dois de setembro a dois de dezembro. O estágio serviu como processo de consolidação dos conhecimentos obtidos...


Extensão universitária e desenvolvimento local : as incubadoras universitárias

Coelho, Hugo

No actual contexto de crise considera-se indispensável uma maior articulação da universidade com a sociedade. A universidade (seja ela pública ou privada) ao invés de se isolar dentro dos seus muros como historicamente tem ocorrido, poderá exercer um papel activo nos rumos e destinos do país, através das suas principais funções: ensino, investigação e extensão. Este artigo aborda esta última função - a extensão...


Prediction of entrepreneurship : an ordered regression approach

Silva, Francisco; Couto, Gualter; Coelho, Hugo

Entrepreneurship is a popular research topic over the last several decades. Various authors study the characteristics that best define future entrepreneur profiles. In this paper, we apply a framework to screen school populations in the Azores Islands, Portugal, for prospects of entrepreneurship and to study the profiles of those who show noticeably entrepreneurial orientations. The contribution of the paper co...


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