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Rational selection of hidden epitopes for a molecularly imprinted electrochemic...
Silva, Matheus Siqueira; Tavares, Ana Patricia Moreira; Coelho, Luiz Felipe Leomil; Dias, Lígia Ely Morganti Ferreira; Chura-Chambi, Rosa MariaRational selection of predicted peptides to be employed as templates in molecular imprinting was carried out for the heat-denatured non-structural protein 1 (NS1) of dengue virus (DENV). Conservation analysis among 301 sequences of Brazilian isolates of DENV and zika virus (ZIKV) NS1 was carried out by UniProtKB, and peptide selection was based on in silico data of the conservational, structural and immunogenic...
Synthesis, activity and docking studies of eugenol-based glucosides as new agen...
Santos, Marcelo Henrique dos; Hipólito, Taciane Maíra Magalhães; Bastos, Guilherme Tadeu Lemos; Barbosa, Thúlio Wliandon LemosSeventeen new synthetic derivatives of eugenol (6, 8–15 and 8′‐15′) were planned following literature reports on antifungal activities of nitroeugenol and eugenol glucoside. The anti‐Candida activity of these compounds was investigated by in vitro assay and the cytotoxicity evaluation was performed with the most active compounds. The peracetylated glucosides presented better biological results than their hydrox...
Genes that encodes NAGT, MIF1 and MIF2 are not virulence factors for kala-azar ...
Aguiar, Bruno Guedes Alcoforado; Coelho, Daniela Lemos; Costa, Dorcas Lamounier; Drumond, Betânia Paiva; Coelho, Luiz Felipe LeomilMade available in DSpace on 2015-02-02T12:39:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-10-01Bitstream added on 2015-02-02T13:08:18Z : No. of bitstreams: 1 S0037-86822014000500593.pdf: 761345 bytes, checksum: 0ef1c74ecc813741230004f4f68aa7a0 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Ap...
EVALUATION OF ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF PLANT EXTRACTS FROM SOU...
Chavasco, Juliana Moscardini; Prado E Feliphe, Barbara Helena Muniz; Cerdeira, Claudio Daniel; Leandro, Fabricio Damasceno; Coelho, Luiz Felipe LeomilFoi avaliada a atividade antimicrobiana de extratos hidroetanólicos de plantas sobre bactérias Gram positiva, Gram negativa, leveduras, Mycobacterium tuberculosis H37 e Mycobacterium bovis pela técnica de difusão em Agar e microdiluição em caldo. Dentre os extratos avaliados pelo método de difusão em Agar, o extrato da folha de Bidens pilosa apresentou a mais expressiva média de halos de inibição de crescimento...
PREVALENCE OF PARACOCCIDIOIDOMYCOSIS INFECTION BY INTRADERMAL REACTION IN RURAL...
Magalhães, Evandro Monteiro de Sá; Ribeiro, Carla de Fátima; Dâmaso, Carla Silva; Coelho, Luiz Felipe Leomil; Silva, Roberta RibeiroThis study aimed to estimate the prevalence of paracoccidioidal infection by intradermal reaction (Delayed-Type Hypersensitivity, DTH) to Paracoccidioides brasiliensis in rural areas in Alfenas, Southern Minas Gerais (MG) State, Brazil, and to assess risk factors (gender, occupation, age, alcohol intake and smoking) associated with infection. We conducted a population-based cross-sectional study using intraderm...
Identification of blood meal sources of Lutzomyia longipalpis using polymerase ...
Soares, Vítor Yamashiro Rocha; Silva, Jailthon Carlos Da; Silva, Kleverton Ribeiro Da; Cruz, Maria Do Socorro Pires E; Santos, Marcos Pérsio DantasMade available in DSpace on 2014-10-01T13:08:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-06-01Bitstream added on 2014-10-01T14:03:52Z : No. of bitstreams: 1 S0074-02762014000300379.pdf: 808793 bytes, checksum: e36443e66dcec917b43c5d0ef7e26e56 (MD5); An analysis of the dietary content of haematophagous insects can provide important information about the transmission networks of certain zoonoses. Th...