2 documents found, page 1 of 1
Nanotechnology-Ocular Devices for Glaucoma Treatment: A Literature Review
Cardigos, J; Ferreira, Q; Crisóstomo, S; Coelho, N; Cunha, JP; Abegão Pinto, L; Ferreira, JNanotechnology enabled the development of materials and devices with great utility in different fields of medicine. By using engineered-based nano-devices and structures, human biological systems may be controlled and repaired at a molecular scale, ultimately leading to a biological benefit. In particular, in the field of glaucoma treatment, nanotechnology may, for example, enhance drug residence time on the oc...
Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease
Gonçalves-Dias, C; Morello, J; Correia, MJ; Coelho, N; Antunes, A; Macedo, MP; Monteiro, E; Soto, K, et al.BACKGROUND: The recent growing evidence that the proximal tubule underlies the early pathogenesis of diabetic kidney disease (DKD) is unveiling novel and promising perspectives. This pathophysiological concept links tubulointerstitial oxidative stress, inflammation, hypoxia, and fibrosis with the progression of DKD. In this new angle for DKD, the prevailing molecular mechanisms on proximal tubular cells emerge ...