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ZIKV Strains Elicit Different Inflammatory and Anti-Viral Responses in Microgli...

Oliveira, Fernanda Bellaniza Caminha de; Freire, Vanessa Paola Alves Sampaio de Sá; Coelho, Sharton Vinicius Antunes; Meuren, Lana Monteiro

In recent years, the Zika Virus (ZIKV) has caused pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZS). Although all strains associated with worldwide outbreaks derive from the Asian lineage, the reasons for their enhanced spread and severity are not fully understood. In this study, we conducted a comparative analysis of miRNAs (miRNA-155/146a/124) and their cellular targets (SOCS1/3...


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