2 documents found, page 1 of 1
Transitional metaplasia in intestinal epithelium of rats submitted to intestina...
Santos,Alessandra Marques dos; Coelho,Joao Paulo Ferreira; Juanes,Camila de Carvalho; Azevedo,Rafael Barbosa de; Diniz,Clara AraujoAbstract Purpose: To evaluated the effects of L-lysine on the intestinal and urothelial epithelia in cystoplasty in rats. Methods: Twenty-eight 9-week-old rats were assigned to 4 groups: Group A (n=8) cystoplasty followed by administration of L-lysine (150 mg/kg body weight by gavage) for 30 weeks; Group B (n=8) cystoplasty + water for 30 weeks; Group C (n=6) L-lysine for 30 weeks; Group D (n=6) water for 30 we...
Carcinogenesis in rats subjected to a new model ureterosigmoidostomy and treate...
Santos,Alessandra Marques dos; Coelho,Joao Paulo Ferreira; Juanes,Camila de Carvalho; Azevedo,Rafael Barbosa de; Melo,Nayanna de Oliveira RamosABSTRACT PURPOSE: To evaluate the effects of L-lysine on the intestinal and urothelial epithelium of rats subjected to ureterosigmoidostomy (new model for surgical carcinogenesis). METHODS: Forty-two rats, 9 weeks of age, were divided into 6 groups. Animals in groups A, B, C were subjected to ureterosigmoidostomy (US) and treated with L-lysine, celecoxib and H2O, respectively. Groups D, E and F (non-operated co...