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Thymic function as a predictor of immune recovery in chronically HIV-infected p...

Rb-Silva, Rita; Nobrega, Claudia; Azevedo, Cecilia; Athayde, Emilia; Canto-Gomes, João; Ferreira, Ivo; Cheynier, Rémi; Yates, Andrew J.; Horta, Ana

Poor immunological responders (PIR) are HIV-infected patients with virologic suppression upon antiretroviral therapy (ART) but persistently low CD4+ T cell counts. Early identification of PIR is important given their higher morbimortality compared to adequate immune responders (AIR). In this study, 33 patients severely lymphopenic at ART onset, were followed for at least 36 months, and classified as PIR or AIR ...


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