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The European response to control and manage multi- and extensively drug-resista...

Cole, Michelle J; Day, Michaela; Jacobsson, Susanne; Amato-Gauci, Andrew J; Spiteri, Gianfranco; Unemo, Magnus; European Gonorrhoea Response Plan Group

Because cefixime and ceftriaxone resistance in Neisseria gonorrhoeae and gonorrhoea treatment failures were increasing, a response plan to control and manage multidrug-resistant N. gonorrhoeae (MDR-NG) in Europe was published in 2012. The three main areas of the plan were to: (i) strengthen surveillance of antimicrobial resistance (AMR), (ii) implement monitoring of treatment failures and (iii) establish a comm...


Associations between antimicrobial susceptibility/resistance of Neisseria gonor...

Jacobsson, Susanne; Cole, Michelle J; Spiteri, Gianfranco; Day, Michaela; Unemo, Magnus; Euro-GASP Network

Background: The emergence and spread of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, nationally and internationally, is a serious threat to the management and control of gonorrhoea. Limited and conflicting data regarding the epidemiological drivers of gonococcal AMR internationally have been published. We examined the antimicrobial susceptibility/resistance of gonococcal isolates (n = 15,803) collec...


The European gonococcal antimicrobial surveillance programme (Euro-GASP) approp...

Cole, Michelle J; Quinten, Chantal; Jacobsson, Susanne; Day, Michaela; Amato-Gauci, Andrew J; Woodford, Neil; Spiteri, Gianfranco; Unemo, Magnus

Background: European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP) antimicrobial resistance (AMR) data are used to inform gonorrhoea treatment guidelines; therefore the data need to be robust and representative. We assessed the extent to which Euro-GASP reflects national measures of the AMR situation for Neisseria gonorrhoeae across the European Union/European Economic Area (EU/EEA). Methods: We c...


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