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Comparative study of two histopathological classifications for oral squamous ce...
Longo,Bruna Cristina; Pereira,Emylle Caroline B. F.; Rossi,Débora Cecília N.; Pereira,Leonardo S.; Coletta,Ricardo D.; Morais,Carlos F.; Calone,Iris S.ABSTRACT Introduction: Squamous cell carcinoma (SCC) is the most common tumor among all cancers in the oral cavity. Despite advances, the prognosis of this neoplasm remains a challenge for professionals. Faced with this situation, several studies try to associate the histopathological analysis with prognosis, so that therapeutic planning becomes more accurate. Objectives: This research aimed to conduct an epide...
Uncommon Oral Cleft in Wolf-Hirschhorn Syndrome
Aquino,Sibele Nascimento de; Machado,Renato A.; Paranaíba,Lívia Maris R.; Coletta,Ricardo D.; Aguiar,Marcos J. Burle de; Fernandes,CassandroWolf-Hirschhorn syndrome (WHS) is a syndrome with craniofacial and systemic abnormalities, which is related to 4p deletion. A 3-month old girl with an undiagnosed syndrome was referred for evaluation of the cleft lip and palate. Hypotonia, short stature, cardiac malformation, hypertrophied clitoris, and atypical thumb of both hands was observed. Microcephaly, low-set ear, prominent glabella, downslanting palpeb...
Goldenhar syndrome: clinical features with orofacial emphasis
Martelli-Júnior,Hercílio; Miranda,Roseli Teixeira de; Fernandes,Cassandro Moreira; Bonan,Paulo Rogério Ferreti; Paranaíba,Lívia Máris RibeiroOBJECTIVES: Goldenhar syndrome (GS) is a relatively common developmental disorder characterized by craniofacial anomalies in association with vertebral, cardiac, renal, and central nervous system defects. This paper describes GS features with special emphasis on oral characteristics. MATERIAL AND METHODS: The clinical features of 6 patients with GS aged 3 months to 12 years are described, and a brief review of ...
Expression and Activity of Matrix Metalloproteinase-2 (MMP-2) in the developmen...
Cotrim,Paola; Andrade,Cleverton Roberto de; Line,Sergio; Almeida,Oslei Paes de; Coletta,Ricardo D.Tooth germ development is associated with morphological and biochemical changes of the dental papilla and enamel organ. Enzymes with gelatinolytic activities were studied by semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) and enzymography in tooth germ of newborn to 15-day-old rats. Three major bands with gelatinolytic activity were detected at all periods and characterized as the late...