6 documents found, page 1 of 1
Characterization and bioactivity of copaiba essential oil carried in a self-nan...
Ames-Sibin, Ana Paula; Chagas, Any C.; Ferreira, Sabrina B.S.; Mandim, Filipa; Finimundy, Tiane C.; Calhelha, Ricardo C.; Peralta, Rosane M.Copaiba essential oil (CEO) is the volatile part of copaiba balsam, which has been topically used for various inflammatory conditions. However, there are some concerns about the CEO safety for oral use. The lipophilic character of CEO also limits its application in the pharmaceutical field. This study prepared a selfnanoemulsifying drug delivery system (SNEDDS) containing CEO and evaluated its toxic effects aga...
A critical appraisal of the most recent investigations on the hepatoprotective ...
Garcia-Manieria, Jéssica A.A.; Correa, Vanesa G.; Backes, Emanueli; Sa-Nakanishi, Anacharis Babeto de; Bracht, Lívia; Comar, Jurandir FernandoConventional treatments for liver diseases are often burdened by side effects caused by chemicals. For minimizing this problem, the search for medicines based on natural products has increased. The objective of this review was to collect data on the potential hepatoprotective activity of plants of the Brazilian native flora. Special attention was given to the modes of extraction, activity indicators, and identi...
Pterostilbene influences glycemia and lipidemia and enhances antioxidant status...
de Morais, Juliana Maria Bitencourt; Cruz, Ellen Mayara Souza; da Rosa, Carlos Vinícius Dalto; Cesário, Roberta Carvalho [UNESP]Made available in DSpace on 2021-06-25T10:49:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-15; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Aims: The present study investigated the potential effects of pterostilbene (PT) on glycemic and lipid profiles, fat storage, cardiovascular indices, and hepatic parameters of rats fed with sucrose solution. Main methods: 24 male Wist...
Effects of a Myrciaria jaboticaba peel extract on starch and triglyceride absor...
Castilho, Pâmela Alves; Bracht, Lívia; Barros, Lillian; Albuquerque, Bianca R.; Dias, Maria Inês; Ferreira, Isabel C.F.R.; Comar, Jurandir FernandoThe purpose of this study was to perform a parallel and comparative investigation of the effects of a Myrciaria jaboticaba (common name jabuticaba) peel extract and of its constituent cyanidin-3-O-glucoside on the overall process of starch and triglyceride intestinal absorption. The peel extract inhibited both the porcine pancreactic α-amylase and the pancreatic lipase but was 13.6 times more potent on the latt...
Long-term sucrose solution consumption causes metabolic alterations and affects...
Cruz, Ellen Mayara Souza; Morais, Juliana Maria Bitencourt De; Rosa, Carlos Vinícius Dalto Da; Simoes, Mellina Da Silva; Comar, Jurandir FernandoMade available in DSpace on 2020-12-12T02:01:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; As the number of overweight and obese people has risen in recent years, there has been a parallel increase in the number of peoplewithmetabolic syndrome, diabetes and non-alcoholic fatty liver disease. The consumption of artificially sweetened beverages contributes to these epidemics. This study investi...
Glutamine dipeptide supplementation improves clinical responses in patients wit...
Krupek, Tuane; Silva, Maria Angélica Rafaini Covas Pereira da; Sant´Ana, Débora de Mello Gonçalves; Batista, Márcia ReginaThe effect of glutamine dipeptide (GDP) supplementation in patients with diabetic foot syndrome was evaluated. A total of 22 patients took part in the study. GDP was supplied in 10 g sachets, and was dissolved in water immediately before use, with ingestion once a day, after lunch or after dinner (20 g/day) over a period of 30 days. Quantification of foot insensitive areas, oxidative stress, blood cytokines, an...