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Factors associated with depressive symptoms in older adults in context of socia...
Didoné,Letícia Souza; Jesus,Isabela Thaís Machado de; Santos-Orlandi,Ariene Angelini; Pavarini,Sofia Cristina Iost; Orlandi,Fabiana de SouzaABSTRACT Objective: To identify factors associated with depressive symptoms in the elderly inserted in a context of high social vulnerability. Methods: A cross-sectional study was carried out with 302 elderly people enrolled in Primary Care. We used a sociodemographic questionnaire, Geriatric Depression Scale, Mini Nutritional Assessment, Shor-form-6D Quality of Life Questionnaire and Medical Outcome Study Scal...
Effects of blocking αvβ3 integrin by a recombinant RGD disintegrin on remodelin...
Oliveira,Claudio Ricardo de; Marqueti,Rita de Cassia; Cominetti,Marcia Regina; Douat,Estela Sant'Ana Vieira; Ribeiro,Juliana UemaPURPOSE: To investigate the changes induced by DisBa-01 on repair of wound healing after induced incisional hernia (IH) in rats. METHODS: Thirty two male albino rats were submitted to IH and divided into four experimental groups: G1, placebo control; G2, DisBa-01-treated; G3, anti-αvβ3 antibodies-treated and G4, anti-α2 antibodies-treated. Histological, biochemical and extracellular matrix remodeling analysis o...
Effects of Blocking αvβ3 integrin by a recombinant RGD disintegrin on remodelin...
Oliveira,Claudio Ricardo de; Marqueti,Rita de Cassia; Cominetti,Marcia Regina; Vieira,Estela Sant Ana; Ribeiro,Juliana Uema; Pontes,Carmen Lucia SallaPURPOSE: Incisional hernia (IH) is characterized by defective wound healing process. Disba-01, a αvb3 integrin blocker has shown to control the rate of wound repair and therefore it could be a target for new wound healing therapies.The objective of the study was to determine the changes induced by Disba-01 on repair of wound healing after induced IH in rats. METHODS: Thirty two male albino rats were submitted t...