2 documents found, page 1 of 1
Addressing critical fungal pathogens under a one health perspective: key insigh...
Sabino, R.; Antunes, F.; Araújo, R.; Bezerra, A. R.; Brandão, J.; Carneiro, C.; Carvalho, Agostinho; Carvalho, D.; Conceição, I. C.; Cota Medeiros, F.Fungal infections have emerged as a significant public health concern, especially with the increasing incidence of severe mycoses caused by pathogens such as Aspergillus fumigatus, Candida auris, Candida albicans, and Cryptococcus neoformans. These fungi, listed as critical priorities by the World Health Organization, pose a heightened risk due to rising antifungal resistance and their severe impact on immunoco...
The evolution of a conjugative plasmid and its ability to increase bacterial fi...
Gordo, I.; Fernandes, Lisete; Marques, A. C. R.; Conceição, I. C.; Dionisio, F.Conjugative plasmids are extra-chromosomal DNA elements that are capable of horizontal transmission and are found in many natural isolated bacteria. Although plasmids may carry beneficial genes to their bacterial host, they may also cause a fitness cost. In this work, we studied the evolution of the R1 plasmid and we found that, in spite of the R1 plasmid conferring an initial cost to its host, after 420 genera...