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Toxicological evaluation of lactose and chitosan delivered by inhalation

De Jesus D J Valle; Dinis Oliveira, RJ; Carvalho, F; Bastos, ML; Sanchez S Navarro

These days, inhalation constitutes a promising administration route for many drugs. However, this route exhibits unique limitations, and formulations aimed at pulmonary delivery should include as few as possible additives in order to maintain lung functionality. The purpose of this work was to investigate the safety of lactose and chitosan to the pulmonary tissue when delivered by inhalation. The study was carr...

Date: 2008 | Origin: Repositório Aberto da Universidade do Porto

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