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Exploring Cannabidiol (CBD) and Cannabigerol (CBG) Safety Profile and Skincare ...

Luz-Veiga, M; Mendes, A; Tavares-Valente, D; Amorim, M; Conde, A; Pintado, ME; Moreira, HR; Azevedo-Silva, J; Fernandes, J

Cannabinoids have long been known for their bioactive properties, with their topical application as anti-inflammatory compounds being at the forefront of research for the past decade. Concurrently, the cosmetic market is a fast-growing industry in constant need of new biomolecules. In this work, we studied the safety profile for topical applications of two cannabinoids: cannabidiol (CBD) and cannabigerol (CBG) ...

Date: 2024   |   Origin: Lusíadas Saúde

Women's perinatal depression: Anhedonia-related symptoms have increased in the ...

Costa, R; Pinto, TM; Conde, A; Mesquita, A; Motrico, E; Figueiredo, B

Background: The prevalence of perinatal depression increased during the COVID-19 pandemic, which may be due to changes in the profile of specific depressive symptoms.Aims: To analyze the impact of the COVID-19 pandemic on the (1) prevalence and severity of specific depressive symptoms; and on the (2) prevalence of clinically significant symptoms of depression during pregnancy and postpartum.Methods: Pregnant an...


Anxiety and depressive symptoms effects on cortisol trajectories from pregnancy...

Conde, A; Costa, R; Figueiredo, B

Anxiety and depressive symptoms may influence cortisol trajectories in women and men during pregnancy and the postpartum period. Using a multilevel approach, anxiety and depressive symptoms effects on 24-hour urinary free cortisol trajectories from the 2nd trimester to 3-months postpartum were examined in a sample of 66 women and 65 men with no known psychosocial or medical risk (N = 131; 33 (50%) of them were ...


Sweet cherry (Prunus avium L.) PAPIP1;4 is a functional aquaporin upregulated b...

Breia, R; Mósca, AF; Conde, A; Correia, S; Conde, C; Noronha, H; Soveral, G; Gonçalves, B; Gerós, H

The involvement of aquaporins in rain-induced sweet cherry (Prunus avium L.) fruit cracking is an important research topic with potential agricultural applications. In the present study, we performed the functional characterization of PaPIP1;4, the most expressed aquaporin in sweet cherry fruit. Field experiments focused on the pre-harvest exogenous application to sweet cherry trees, cultivar Skeena, with a sol...


VvSWEET7 Is a Mono- and Disaccharide Transporter Up-Regulated in Response to Bo...

Breia, R; Conde, A; Pimentel, D; Conde, C; Fortes, AM; Granell, A; Gerós, H

The newly-identified SWEETs are high-capacity, low-affinity sugar transporters with important roles in numerous physiological mechanisms where sugar efflux is critical. SWEETs are desirable targets for manipulation by pathogens and their expression may be transcriptionally reprogrammed during infection. So far, few plant SWEET transporters have been functionally characterized, especially in grapevine. In this s...


Intoxicação por Monóxido de Carbono

Conde, A; Alegria, A; Neto, A

O monóxido de carbono é uma das principais causas de intoxicação, podendo ser letal ou levar a sequelas neuropsicológicas tardias. A intoxicação manifesta-se por sintomas pouco especificos, pelo que o seu diagnóstico exige um elevado índice de suspeição. 0 doseamento de carboxihemoglobina e útil, mas apresenta uma fraca correlação quer com a clínica, quer com o prognóstico. O tratamento baseia-se na oxigenação ...


Revascularization and reimplantation of the upper extremity. 15-year-experience...

Malheiro, E; Amarante, J; Reis, J; Silva, A; Conde, A; Choupina, M

Progress in micro or macro replantation has resulted in higher survival rates of formerly amputated parts. More amputated digits or limbs survive because the time of ischemia can be exceeded by using cold storage or perfusion. Homo or heterodigital vessel transposition, expanded indications for vein graft interposition, as well as heterotopic transplantation allow for extremity preservation even in crush injuri...

Date: 1998   |   Origin: Acta Médica Portuguesa

Microsurgical reconstruction of the upper extremity. Experience with 24 free fl...

Costa, H; Pinto, A; Cunha, C; Conde, A; Guimarães, I; Pinho, C; Martins, A; Amarante, J

The authors present the experience of 24 clinical cases of microsurgical reconstruction of the upper limb. These reconstructions were accomplished by different microvascular free flaps which were selected according to the type, size and location of the defects, having applied fasciocutaneous, adipofascial, myo, myocutaneous, tendofasciocutaneous, omentum flaps and 2nd toe transfers. The etiology was traumatic i...

Date: 1998   |   Origin: Acta Médica Portuguesa

Microsurgical reconstruction of the head and neck: experience of 63 free flaps.

Costa, H; Guimarães, I; Cunha, C; Conde, A; Luz, M; Pinto, A; Pinho, C; Freitas, A; Rodrígues, J; Guimarães, A; Trigo, J; Rangel, C; Cruzeiro, C

The authors present the experience of 63 clinical cases of microsurgical reconstruction of the head and neck. These reconstructions were accomplished by different microvascular free flaps which were selected according to the type, size and location of the defects. Fasciocutaneous, osteofasciocutaneous, adipofascial, myo, myocutaneous, myosseous, jejunum and great omentum flaps were applied. The etiology was tra...

Date: 1998   |   Origin: Acta Médica Portuguesa

Reconstruction of the anterior cranial base with a frontal muscle flap in cereb...

Costa, H; Cunha, C; Conde, A; Cerejo, A; Baptista, A; Vaz, R; Gonçalves, M

Craniofacial infection is a major problem for the plastic and neurosurgical team. Previous successful experiences with free muscle and omentum flaps and the galea frontalis myofascial flap have been reported, avoiding disastrous complications after frontofacial advancements and the resection of skull base tumors. The authors report the clinical use of the galea frontalis myofascial flap in the treatment of ante...

Date: 1997   |   Origin: Acta Médica Portuguesa

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