5 documents found, page 1 of 1
Towards user-centered design of medical devices for SUDEP prediction and preven...
Ferreira, J; França, M; Rei, M; Peixoto, R; Armand Larsen, S; Bernini, A; Lopes, L; Conde, C; Claro, JObjectives: As epilepsy management medical devices emerge as potential technological solutions for prediction and prevention of sudden death in epilepsy (SUDEP), there is a gap in understanding the features and priorities that should be included in the design of these devices. This study aims to bridge the gap between current technology and emerging needs by leveraging insights from persons with epilepsy (PWE) ...
Sweet cherry (Prunus avium L.) PAPIP1;4 is a functional aquaporin upregulated b...
Breia, R; Mósca, AF; Conde, A; Correia, S; Conde, C; Noronha, H; Soveral, G; Gonçalves, B; Gerós, HThe involvement of aquaporins in rain-induced sweet cherry (Prunus avium L.) fruit cracking is an important research topic with potential agricultural applications. In the present study, we performed the functional characterization of PaPIP1;4, the most expressed aquaporin in sweet cherry fruit. Field experiments focused on the pre-harvest exogenous application to sweet cherry trees, cultivar Skeena, with a sol...
VvSWEET7 Is a Mono- and Disaccharide Transporter Up-Regulated in Response to Bo...
Breia, R; Conde, A; Pimentel, D; Conde, C; Fortes, AM; Granell, A; Gerós, HThe newly-identified SWEETs are high-capacity, low-affinity sugar transporters with important roles in numerous physiological mechanisms where sugar efflux is critical. SWEETs are desirable targets for manipulation by pathogens and their expression may be transcriptionally reprogrammed during infection. So far, few plant SWEET transporters have been functionally characterized, especially in grapevine. In this s...
Phosphatases in Mitosis: Roles and regulation
Moura, M; Conde, CMitosis requires extensive rearrangement of cellular architecture and of subcellular structures so that replicated chromosomes can bind correctly to spindle microtubules and segregate towards opposite poles. This process originates two new daughter nuclei with equal genetic content and relies on highly-dynamic and tightly regulated phosphorylation of numerous cell cycle proteins. A burst in protein phosphorylat...
Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Che...
Moura, M; Osswald, M; Leça, N; Barbosa, J; Pereira, AJ; Maiato, H; Sunkel, CE; Conde, CFaithfull genome partitioning during cell division relies on the Spindle Assembly Checkpoint (SAC), a conserved signaling pathway that delays anaphase onset until all chromosomes are attached to spindle microtubules. Mps1 kinase is an upstream SAC regulator that promotes the assembly of an anaphase inhibitor through a sequential multi-target phosphorylation cascade. Thus, the SAC is highly responsive to Mps1, w...