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Tailored Perioperative Medicine For Frail Patients Undergoing Vascular Surgery:...

Miguel, Bernardo; Oliveira, Sarah; Valente Jorge, João; Conde, Patrícia; Alves, Ângela

Frailty is a concept that is emerging as an important tool in the preoperative assessment of patients. The incidence of frailty in vascular surgery patients is high and is expected to increase concomitantly with the aging of the population. The identification of these patients and their optimization in the perioperative period can lead to an improvement in their outcomes with a reduction in morbidity and mortal...


Programa Nacional de Vigilância da Gripe: relatório da época 2019/2020

Pechirra, Pedro; Cristóvão, Paula; Costa, Inês; Conde, Patrícia; Silva, Susana; Torres, Ana Rita; Machado, Ausenda; Rodrigues, Ana Paula

Relatório anual do Programa Nacional de Vigilância da Gripe (PNVG). A presente publicação descreve a caraterização clínica e laboratorial da atividade gripal na época 2019/2020. O PNVG assegura a vigilância epidemiológica da gripe em Portugal, integrando as componentes de vigilância clínica e laboratorial. A componente clínica possibilita o cálculo de taxas de incidência permitindo descrever a intensidade e evo...


Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 6...

Kissling, Esther; Hooiveld, Mariette; Sandonis Martín, Virginia; Martínez-Baz, Iván; William, Naoma; Vilcu, Ana-Maria; Mazagatos, Clara; Domegan, Lisa

The I-MOVE-COVID-19 network collates epidemiological and clinical information on patients with coronavirus disease (COVID-19), including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virological characterisation in 11 European countries [1]. One component of I-MOVE-COVID-19 is the multicentre vaccine effectiveness (VE) study at primary care/outpatient level in nine European study sites in eight c...


Influenza vaccine effectiveness estimates using the test-negative design with d...

Gómez, Verónica; Kislaya, Irina; Machado, Ausenda; Pechirra, Pedro; Costa, Inês; Cristóvão, Paula; Conde, Patrícia; Guiomar, Raquel; Nunes, Baltazar

Background: The test-negative design (TND) has been used to monitor influenza vaccine effectiveness (IVE). Negative controls are those that tested negative for any influenza virus - however, there are issues related to the selection of the negative controls; As it is hypothesized a potential bias introduced by virus interference in TND, some authors suggest to use other respiratory virus as control group. Hence...


I-MOVE-COVID-19: uma rede europeia para investigar, prevenir e controlar a pand...

Gómez, Verónica; Machado, Ausenda; Rodrigues, Ana Paula; Kislaya, Irina; Conde, Patrícia; Costa, Inês; Cristóvão, Paula; Verdasca, Nuno; Guiomar, Raquel

Face à pandemia da COVID-19, a vigilância epidemiológica tem um papel fundamental para a deteção precoce de casos e a monitorização da pandemia. A par com a vigilância epidemiológica, importa, também, investigar fatores protetores e de risco para COVID-19, bem como estimar a efetividade de intervenções para controlo da doença, desde a efetividade de intervenções terapêuticas, como a vacina ou de medidas de saúd...


Interim 2019/20 influenza vaccine effectiveness: six European studies, Septembe...

Rose, Angela; Kissling, Esther; Emborg, Hanne-Dorthe; Larrauri, Amparo; McMenamin, Jim; Pozo, Francisco; Trebbien, Ramona; Mazagatos, Clara

Background: Influenza A(H1N1)pdm09, A(H3N2) and B viruses were co-circulating in Europe between September 2019 and January 2020. Aim: To provide interim 2019/20 influenza vaccine effectiveness (VE) estimates from six European studies, covering 10 countries and both primary care and hospital settings. Methods: All studies used the test-negative design, although there were some differences in other study characte...


Hospital-based test negative case control study to measure seasonal influenza v...

Gómez, Verónica; Kislaya, Irina; Pechirra, Pedro; Conde, Patrícia; Costa, Inês; Cristóvão, Paula; Nunes, Baltazar; Guiomar, Raquel; Machado, Ausenda

Objectives: The aim of the EVA Hospital study was to measure IVE against influenza laboratory confirmed SARI hospitalized in the older adult population at national level and contribute to the European estimate. In specific, it was intended to estimate 2018-19 seasonal influenza VE against SARI laboratoryconfirmed influenza requiring hospitalization, when possible: by age group (65-79 years, 80+ years) and; by p...


Epidemiology and genetic variability of respiratory syncytial virus in Portugal...

Sáez-López, Emma; Cristóvão, Paula; Costa, Inês; Pechirra, Pedro; Conde, Patrícia; Guiomar, Raquel; Peres, Maria João; Viseu, Regina; Lopes, Paulo

Introduction: Respiratory syncytial virus (RSV) is associated with substantial morbidity and mortality since it is a predominant viral agent causing respiratory tract infections in infants, young children and the elderly. Considering the availability of the RSV vaccines in the coming years, molecular understanding in RSV is necessary. Objective: The objective of the present study was to describe RSV epidemiolog...


Estamos protegidos após a vacinação contra a gripe? Resposta imunitária para o ...

Guiomar, Raquel; Rodrigues, Ana Paula; Costa, Inês; Conde, Patrícia; Cristóvão, Paula; Pechirra, Pedro; Estragadinho, Paulo; Nunes, Baltazar

A vacina contra a gripe é hoje a principal forma de prevenção da doença, reduzindo o risco e as complicações associadas à infeção. A vacinação anual é recomendada pela Direção Geral da Saúde (DGS) de acordo com a norma da vacinação contra a gripe. O Instituto Nacional de Saúde, I.P. (INSA) no âmbito da sua missão como laboratório de Estado, das suas competências específicas para a vigilância epidemiológica das ...


Performance of surveillance case definitions for respiratory syncytial virus in...

Sáez-López, Emma; Pechirra, Pedro; Costa, Inês; Cristóvão, Paula; Conde, Patrícia; Machado, Ausenda; Rodrigues, Ana Paula; Guiomar, Raquel

Background: Well-established influenza surveillance systems (ISS) can be used for respiratory syncytial virus (RSV) surveillance. In Portugal, RSV cases are detected through the ISS using the European Union (EU) influenza-like illness (ILI) case definition. Aim: To investigate clinical predictors for RSV infection and how three case definitions (EU ILI, a modified EU acute respiratory infection, and one respira...


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