3 documents found, page 1 of 1
Chrysotila pseudoroscoffensis as a source of high-value polar lipids with antio...
Moreira, Ana S. P.; Gonçalves, Joana; Conde, Tiago A.; Couto, Daniela; Melo, Tânia; Maia, Inês Beatriz; Pereira, Hugo; Silva, JoanaMicroalgae are emerging as sustainable sources of a wide range of high-value compounds. However, the knowledge about microalgae polar lipids is still limited, despite their interest due to their chemical diversity and bioactivity. This study shows, for the first time, the polar lipidome of the haptophyte microalga Chrysotila pseudoroscoffensis unveiled by using hydrophilic interaction liquid chromatography-high...
Effects of outdoor and indoor cultivation on the polar lipid composition and an...
Couto, Daniela; Conde, Tiago A.; Melo, Tânia; Neves, Bruna; Costa, Margarida; Cunha, Pedro; Guerra, Inês; Correia, Nádia; Silva, Joana T.; Pereira, HugoNannochloropsis is a genus of eicosapentaenoic acid-rich microalgae with high levels of value-added polar lipids. However, the polar lipid composition of microalgal biomass is highly dependent on culture conditions (e.g., light or temperature), which are significantly different under indoor and outdoor culture conditions. In this study, we sought to investigate the plasticity of the polar lipid profile of a mar...
Flavonoid-mediated immunomodulation of human macrophages involves key metabolit...
Mendes, Luís F.; Gaspar, Vítor M.; Conde, Tiago A.; Mano, João F.; Duarte, Iola F.The ability of flavonoids to attenuate macrophage pro-inflammatory activity and to promote macrophage-mediated resolution of inflammation is still poorly understood at the biochemical level. In this study, we have employed NMR metabolomics to assess how therapeutically promising flavonoids (quercetin, naringenin and naringin) affect the metabolism of human macrophages, with a view to better understand their bio...