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A functional polymorphism in IL-36β modulates macrophage antifungal effector fu...

Gonçalves, Samuel M.; Leite, L.; de Vasconcelos, P.; Pereira, I.; Dewi, I. M. W.; Mercier, T.; Aerts, R.; Ligeiro, D.; Mendes, F.; Freitas, F.

Background: Genetic predisposition plays a major role in the development of invasive pulmonary aspergillosis (IPA). The risk and course of IPA vary significantly among patients, yet continuously new genetic mechanisms that influence individual antifungal immune responses are being discovered. While genetic variability in interleukin (IL)-1 family cytokines is recognized as an important cause of disease suscepti...


Scale-up of a system for hydrocarbon production by electrochemical reduction of...

Fernandes, T. R. C.; Machado, Ana; Condeço, J.; Rangel, C. M.; Pardal, T.

This work addresses the scaling up of a system for electrochemical reduction of CO2 to produce hydrocarbons that can be used as fuel for a regenerative energy storage cycle. Challenges involved in such a task are mentioned. Scalingup results of a system based on electrodes of high surface area with modified copper deposits are described. Current densities around 100 mA/cm2 were obtained. This corresponds to the...

Date: 2011   |   Origin: Repositório do LNEG

Análise da relação fenótipo/genótipo HLA no transplante renal

Cunha, S.; Dias, M.; Amorim, Manuela; Condeço, J.

A melhor opção terapêutica na maioria dos pacientes em fase final de insuficiência renal é o transplante renal (TR). O estudo da compatibilidade do TR é feito através da caracterização dos antigénios leucocitários humanos (HLA). Neste estudo analisou-se a relação fenótipo/genótipo HLA no TR em 5 pares dador/receptor. Fenotipicamente os pares foram iguais, no entanto, genotipicamente verificou-se a existência de...


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