2 documents found, page 1 of 1
METHODS FOR EXTRACTION AND ISOLATION OF AGATHISFLAVONE FROM POINCIANELLA PYRAMI...
Nascimento,Bruna O. do; David,Jorge M.Agathisflavone is a natural biflavone with restricted occurrence in plants. This biflavone presents several biological activities and can be important to developing new drugs. Obtaining such a molecule on a large scale for in vivo tests is a challenge. To date, there are no reports regarding its synthesis; thus, it is important to improve and develop methods for the purification of this bioactive compound from ...
Bergenin of Peltophorum dubium (Fabaceae) Roots and Its Bioactive Semi-Syntheti...
Silva Neto,Oscar C. da; Teodoro,Marla T. F.; Nascimento,Bruna O. do; Cardoso,Klauber V.; Silva,Eliane O.; David,Jorge M.; David,Juceni P.This work describes the isolation of pure bergenin from Peltophorum dubium roots with good yields and its further derivatization through Williamson synthesis. The alkyl derivatives of the bergenin were identified by nuclear magnetic resonance and mass spectrometry data analysis. Among them, three derivatives were reported for the first time herein, 8,10-dihexyl-bergenin, 8,10-didecyl-bergenin, and 8,10-ditetrad...