Chylothorax in the perinatal period may have congenital or acquired aetiologies. In premature infants, invasive procedures with thrombosis risk are common practice. We present a case of a 29-week gestation neonate, diagnosed on the 27th postnatal day with vegetation on the tip of the central venous catheter (CVC) and right auricle thrombosis, along with superior vena cava (SVC) syndrome, leading to significant ...