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Plasma membrane proteomes of differentially matured dendritic cells identified ...
Bernard, Stéphanie Ferret; Borges, William de Castro; Dowle, Adam A.; Sanin, David E.; Cook, Peter C.; Turner, Joseph D.; MacDonald, Andrew S.Dendritic cells (DCs) play a pivotal role in polarising Th lymphocyte subsets but it is unclear whatmolecular events occur when DCs generate Th2-type responses. Here, we analysed plasma membrane-enriched fractions from immature, pro-Th1 and pro-Th2 DCs and used a combination of iTRAQ labelling and LC–MS/MS to quantify changes in the proteomes. Analysis was performed on triplicate biological samples and changes ...
Date: 2017
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Origin: Oasisbr