14 documents found, page 1 of 2
Adult blaschkolinear acquired inflammatory skin eruption (BLAISE) with simultan...
Raposo, I.; Mota, F.; Fernandes, I.; Canelhas, Á.; Selores, M.Blaschkitis and lichen striatus are generally distinguished in the literature by the age of onset, lesion distribution, and histopathology. However, there is currently no clear consensus among authors about whether to consider blaschkitis and lichen striatus different clinical entities or a spectrum ofthe same disease. We present a case of adult BLAISE with features of both lichen striatus and blaschkitis, whic...
Adult blaschkolinear acquired inflammatory skin eruption (BLAISE) with simultan...
Raposo, I.; Mota, F.; Fernandes, I.; Canelhas, Á.; Selores, M.Blaschkitis and lichen striatus are generally distinguished in the literature by the age of onset, lesion distribution, and histopathology. However, there is currently no clear consensus among authors about whether to consider blaschkitis and lichen striatus different clinical entities or a spectrum ofthe same disease. We present a case of adult BLAISE with features of both lichen striatus and blaschkitis, whic...
Nasolabial flap - alternative uses for a classic but versatile technique
Mota, F.; Horta, M.; Caetano, M.; Costa, V.; Selores, M.The nasolabial flap is one of the most ancient techniques used in orofacial surgery. The authors report two cases of patients with skin cancer treated surgically with variations of the classic nasolabial flap by transposition (bilateral and folded) that highlight the broad applicability of this technique.
Annular elastolytic giant cell granuloma: a "visible" diagnosis
Raposo, I.; Mota, F.; Lobo, I.; Brandão, J.; Selores, M.Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of undetermined cause, characterized by annular plaques with raised erythematous borders in sun-exposed skin. The typical histologic features are dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis. The authors describe a clinical case of AEGCG, which exhibited an excellent response ...
Importance of immunogenicity testing for cost-effective management of psoriasis...
Mota, F.; Neves, E.; Oliveira, J.; Selores, M.; Torres, T.INTRODUCTION: Up to 30% of patients treated with anti-tumor necrosis factor drugs do not respond adequately, and up to 50% lose response over time. Immunogenicity is now known to be one of the main causes of this loss of response. METHODS: Serum levels of adalimumab and anti-drug antibodies (ADAs) were measured in 19 patients with psoriasis. RESULTS: Eighty-nine percent of the patients were responders (Psoriasi...
Primary vulvar Paget disease - the importance of clinical suspicion
Mota, F.; Horta, M.; Marques, C.; Foreid, S.; Selores, M.Extramammary Paget disease of the vulva is a rare condition that accounts for only 1-2% of vulvar malignancies and represents a frequent cause of misdiagnosis. It is most commonly seen in postmenopausal women. Clinically it is similar to Paget disease of the breast, appearing as red, well-demarcated eczematoid lesions, with slightly raised edges. A high degree of clinical suspicion is very important when evalua...
Infantile myofibromatosis - a clinical and pathological diagnostic challenge
Mota, F.; Machado, S.; Moreno, F.; Barbosa, T.; Selores, M.Infantile myofibromatosis is a rare disorder of fibroblastic/myofibroblastic proliferation and represents the most frequent type of mesenchymal tumor in the neonatal period and primary infancy.Three clinical types have been described: solitary, multicentric, and generalized (with visceral involvement). A correct characterization of the histopathology is essential to diagnose these neoplasias in early infancy. W...
Late onset pityriasis rubra pilaris type IV treated with low-dose acitretin
Mota, F.; Carvalho, S.; Sanches, M.; Selores, M.Pityriasis rubra pilaris is a chronic inflammatory dermatosis of unknown etiology and great clinical variability. It has been divided into six categories. Types III, IV, and V occur in childhood and are distinguished by their clinical presentation, age of onset, and course. We report a 19-year-old male patient with a 2-week history of pruritic, scaling dermatosis of the hands, feet, elbows, and knees. He had no...
Plasmablastic lymphoma: an atypical cutaneous presentation of a rare entity
Mota, F.; Mesquita, B.; Carvalho, S.; Coelho, A.; Velho, G.; Lima, M.; Selores, M.Plasmablastic lymphoma is a very rare B-cell lymphoma typically associated with immunosuppression: It occurs primarily in the oral cavity, although some cases were reported in other organs and tissues.To date, only 10 cases of primary cutaneous plasmablastic lymphoma have been described. Clinically, primary cutaneous plasmablastic lymphoma presents as non-specific cutaneous lesions (purple nodules, erythematous...
MELANOMA? LOOK CLOSER
Mota, F.; Lobo, I.; Mahia, Y.; Costa, V.; Selores, M.Pigmented skin lesions are sometimes misdiagnosed due to clinical similarities between melanocytic and non-melanocytic lesions. We report the case of a patient with a pigmented lesion that clinically resembles melanoma. With dermoscopy, observed features, namely leaf-like areas, allowed us to make the diagnosis of pigmented basal cell carcinoma. This case represents a clinical setting in which clinical examinat...