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Synthesis and Antioxidant and Antimicrobial Properties of β-Hydroxy Sulfides, S...

Copini,Suély; Micheletti,Ana C.; Lima,Dênis P. de; Gomes,Roberto S.; Meza,Alisson; Beatriz,Adilson

Natural and synthetic sulfur-bearing organic compounds have many applications in medicinal chemistry. This article reports the preparation of amphiphilic β-hydroxy sulfides, sulfoxides, and sulfones derived from cardanol and glycerol. Thiolysis of cardanol epoxide 3 with various thiols (4a-4j) in ethanol or water yielded the corresponding β-hydroxy sulfides 5a-5j (61-95%). Treatment with 30% H2O2 in acetic acid...

Date: 2020   |   Origin: Oasisbr
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