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A mechanism for red coloration in vertebrates
Toomey, Matthew B.; Marques, Cristiana I.; Araújo, Pedro M.; Huang, Delai; Zhong, Siqiong; Liu, Yu; Schreiner, Gretchen D.; Myers, Connie A.Red coloration is a salient feature of the natural world. Many vertebrates produce red color by converting dietary yellow carotenoids into red ketocarotenoids via an unknown mechanism. Here, we show that two enzymes, cytochrome P450 2J19 (CYP2J19) and 3-hydroxybutyrate dehydrogenase 1-like (BDH1L), are sufficient to catalyze this conversion. In birds, both enzymes are expressed at the sites of ketocarotenoid bi...
Date: 2022
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Origin: Estudo Geral - Universidade de Coimbra